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gspO Type II secretion system prepilin peptidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947840, updated on 2-May-2024

Summary

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Gene symbol
gspO
Gene description
Type II secretion system prepilin peptidase
Primary source
ASAP:ABE-0010901
Locus tag
b3335
See related
ECOCYC:EG11359
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3322; hofD; hopD; hopO; yheC
Summary
GspG is processed by GspO when both are expressed. gspO complements a pulO mutation for pullanase secretion in a K-12 strain with the Klebsiella pul operon. [More information is available at EcoGene: EG11359]. In Escherichia coli, gspO is a member of an operon of genes (gspC-O) which are not normally expressed but are homologous to those encoding the secreton, or type II secretion machinery in Klebsiella oxytoca and Aeromonase hydrophila, among others . [More information is available at EcoCyc: EG11359].
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Genomic context

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Sequence:
NC_000913.3 (3465543..3466220)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene Type II secretion system protein GspJ Neighboring gene Type II secretion system protein GspK Neighboring gene Type II secretion system protein GspL Neighboring gene Type II secretion system protein GspM Neighboring gene bacterioferritin Neighboring gene bacterioferritin-associated ferredoxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria. Whitchurch CB, et al. Gene, 1991 May 15. PMID 1676385
  2. Cloning, sequencing, and mapping of the bacterioferritin gene (bfr) of Escherichia coli K-12. Andrews SC, et al. J Bacteriol, 1989 Jul. PMID 2661540, Free PMC Article
  3. Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake and the assembly of type-4 fimbriae in other bacteria. Whitchurch CB, et al. Gene, 1994 Dec 2. PMID 7959070
  4. Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides. Vignon G, et al. J Bacteriol, 2003 Jun. PMID 12754241, Free PMC Article
  5. Involvement of the twin-arginine translocation system in protein secretion via the type II pathway. Voulhoux R, et al. EMBO J, 2001 Dec 3. PMID 11726509, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Type II secretion system prepilin peptidase
NP_417794.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3465543..3466220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417794.1 Type II secretion system prepilin peptidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417794.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A4C7AZY1
    Conserved Domains (1) summary
    COG1989
    Location:1 → 225
    PulO; Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase [Cell motility, Intracellular trafficking, secretion, and vesicular transport]
Nucleotide Protein
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