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ppa inorganic pyrophosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948748, updated on 11-Oct-2018

Summary

Gene symbol
ppa
Gene description
inorganic pyrophosphatase
Primary source
EcoGene:EG10755
Locus tag
b4226
See related
ASAP:ABE-0013824; ECOCYC:EG10755
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4222
Summary
The enzyme is a hexamer, arranged as a dimer of trimers in the crystal structure . [More information is available at EcoCyc: EG10755].

Genomic context

Sequence:
NC_000913.3 (4449122..4449652, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene gamma-glutamylamine cyclotransferase family protein YtfP Neighboring gene putative YjfA Neighboring gene ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system Neighboring gene endoribonuclease toxin ChpB Neighboring gene galactofuranose ABC transporter periplasmic binding protein Neighboring gene galactofuranose ABC transporter putative ATP binding subunit

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
inorganic diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inorganic diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
magnesium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
triphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
phosphate-containing compound metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
inorganic pyrophosphatase
NP_418647.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4449122..4449652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418647.1 inorganic pyrophosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418647.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A7A9
    Conserved Domains (1) summary
    PRK01250
    Location:1176
    PRK01250; inorganic pyrophosphatase; Provisional
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