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E1 E1 [ Etapapillomavirus 1 ]

Gene ID: 951231, updated on 15-Aug-2018

Summary

Gene symbol
E1
Gene description
E1
Locus tag
FcpVgp2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Etapapillomavirus 1 (acronym: FPV)
Lineage
Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Etapapillomavirus
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Genomic context

Sequence:
NC_004068.1 (714..2798)

NC_004068.1Genomic Context describing neighboring genes Neighboring gene putative E7 protein Neighboring gene putative X-ORF protein Neighboring gene putative regulatory protein E2 Neighboring gene putative minor capsid protein L2 Neighboring gene major capsid L1 protein

General protein information

Preferred Names
E1
NP_663763.1
  • E1; The Papillomaviriuses are icosahedral dsDNA viruses that encode 7 early proteins, E1 to E7, and 2 late structural proteins L1 and L2. Host infection by members of the papillomaviruses gives rise to warts and cancer in some instances. The E1 helicase protein is an ATP-dependent DNA helicase that facilitates the inititiation of viral DNA replication through its interactions with the viral E2 protein. The E1-E2 complex binds to the viral origin of replication where E1 acts to unwind the DNA and E2 acts as a transcriptional activator.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004068.1 Reference assembly

    Range
    714..2798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_663763.1 putative replication protein E1 [Etapapillomavirus 1]

    See identical proteins and their annotated locations for NP_663763.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A193DR40, Q8JNA6
    Conserved Domains (2) summary
    PHA02774
    Location:167669
    PHA02774; E1; Provisional
    cl24009
    Location:249681
    Parvo_NS1; Parvovirus non-structural protein NS1