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Tmem132a transmembrane protein 132A [ Mus musculus (house mouse) ]

Gene ID: 98170, updated on 16-Oct-2021

Summary

Official Symbol
Tmem132aprovided by MGI
Official Full Name
transmembrane protein 132Aprovided by MGI
Primary source
MGI:MGI:2147810
See related
Ensembl:ENSMUSG00000024736
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Orai1; R74613; Hspa5bp1; 6720481D13Rik
Expression
Broad expression in cerebellum adult (RPKM 93.6), whole brain E14.5 (RPKM 86.6) and 17 other tissues See more
Orthologs
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Genomic context

See Tmem132a in Genome Data Viewer
Location:
19; 19 A
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10835193..10847569, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10857829..10870205, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (10932319..10944269, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A430093F15 gene Neighboring gene CD6 antigen Neighboring gene solute carrier family 15, member 3 Neighboring gene transmembrane protein 109 Neighboring gene pre-mRNA processing factor 19

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in negative regulation of programmed cell death ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 132A
Names
HSPA5-binding protein 1
heat shock 70kDa protein 5 binding protein 1
heat shock protein 5 binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378918.1NP_001365847.1  transmembrane protein 132A isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC132402
    Conserved Domains (3) summary
    pfam15705
    Location:44167
    TMEM132D_N; Mature oligodendrocyte transmembrane protein, TMEM132D, N-term
    pfam15706
    Location:831896
    TMEM132D_C; Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
    pfam16070
    Location:404746
    TMEM132; Transmembrane protein family 132
  2. NM_133804.2NP_598565.2  transmembrane protein 132A isoform 1 precursor

    See identical proteins and their annotated locations for NP_598565.2

    Status: VALIDATED

    Source sequence(s)
    AK048556, AK173207, CF729397
    Consensus CDS
    CCDS29589.1
    UniProtKB/Swiss-Prot
    Q922P8
    Related
    ENSMUSP00000025645.8, ENSMUST00000025645.14
    Conserved Domains (3) summary
    pfam15705
    Location:44167
    TMEM132D_N; Mature oligodendrocyte transmembrane protein, TMEM132D, N-term
    pfam15706
    Location:830897
    TMEM132D_C; Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
    pfam16070
    Location:403744
    TMEM132; Transmembrane protein family 132

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10835193..10847569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003952832.1 RNA Sequence

    Related
    ENSMUST00000120524.2
  2. XR_386529.3 RNA Sequence

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