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    Trp53-ps transformation related protein 53, pseudogene [ Mus musculus (house mouse) ]

    Gene ID: 22060, updated on 31-Mar-2024

    Summary

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    Official Symbol
    Trp53-psprovided by MGI
    Official Full Name
    transformation related protein 53, pseudogeneprovided by MGI
    Primary source
    MGI:MGI:98835
    See related
    AllianceGenome:MGI:98835
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
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    Genomic context

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    Location:
    17 C; 17 28.3 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (54726625..54728264)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (54419597..54421236)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700025K24 gene Neighboring gene predicted gene, 52325 Neighboring gene STARR-seq mESC enhancer starr_42858 Neighboring gene STARR-seq mESC enhancer starr_42859 Neighboring gene myo-inositol 1-phosphate synthase A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_42860 Neighboring gene predicted gene, 26291

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells]. Liu HY, et al. Sheng Li Xue Bao, 2023 Feb 25. PMID 36859831
    2. BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma. Chen SJ, et al. Cell Commun Signal, 2023 Feb 20. PMID 36803515, Free PMC Article
    3. Interdependent Nuclear Co-Trafficking of ASPP1 and p53 Aggravates Cardiac Ischemia/Reperfusion Injury. Yang Y, et al. Circ Res, 2023 Jan 20. PMID 36656967, Free PMC Article
    4. A single gene and a pseudogene for the cellular tumour antigen p53. Zakut-Houri R, et al. Nature, 1983 Dec 8-14. PMID 6646235
    5. The gene and the pseudogene for mouse p53 cellular tumor antigen are located on different chromosomes. Czosnek HH, et al. Mol Cell Biol, 1984 Aug. PMID 6387444, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
      Title: p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
    2. Kielin/chordin-like protein deficiency aggravates pressure overload-induced cardiac dysfunction and remodeling via P53/P21/CCNB1 signaling in mice.
      Title: Kielin/chordin-like protein deficiency aggravates pressure overload-induced cardiac dysfunction and remodeling via P53/P21/CCNB1 signaling in mice.
    3. CK1alpha deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3beta pathway and inhibiting Foxa2 expression through p53 pathwaydagger.
      Title: CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
    4. Regulation of the innate immune response and gut microbiome by p53.
      Title: Regulation of the innate immune response and gut microbiome by p53.
    5. p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.
      Title: p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.
    6. HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
      Title: HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
    7. Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/beta-catenin signaling.
      Title: Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.
    8. p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism.
      Title: p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism.
    9. E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.
      Title: E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.
    10. [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells].
      Title: [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells].
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    General gene information

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    Markers

    Other Names

    • p53-variant

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_001473.4 

      Range
      101..1740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      54726625..54728264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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