| Results showed that Tie-2 mRNA and protein expression from the eutopic endometrium did not differ significantly between endometriosis patients and normal controls. | Angiopoietin-1, angiopoietin-2 and Tie-2 expression in eutopic endometrium in advanced endometriosis.
Hur SE, Lee JY, Moon HS, Chung HW. | 01/21/2010 |
| sAng-2 and sTie-2 play a role in progression of some haematological malignancies | Differential levels of soluble angiopoietin-2 and Tie-2 in patients with haematological malignancies.
Quartarone E, Alonci A, Allegra A, Bellomo G, Calabrò L, D'Angelo A, Del Fabro V, Grasso A, Cincotta M, Musolino C. | 01/21/2010 |
| tyrosine residue 1106 on Tie2 is critical for coupling downstream cell migration signal transduction pathways with Angiopoietin 1 stimulation in endothelial cells | A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function.
Jones N, Chen SH, Sturk C, Master Z, Tran J, Kerbel RS, Dumont DJ., Free PMC Article | 01/21/2010 |
| Tie-2 receptor is expressed by human neutrophils whose active site ligation with either angiopoietin-1 or angiopoietin-2 exerts migratory effects on the one hand and arrests VEGF-mediated chemotaxis on the other | Angiopoietin affects neutrophil migration.
Sturn DH, Feistritzer C, Mosheimer BA, Djanani A, Bijuklic K, Patsch JR, Wiedermann CJ. | 01/21/2010 |
| expression and function of TIE2 in hematopoietic stem cells in cord blood | Analysis of human TIE2 function on hematopoietic stem cells in umbilical cord blood.
Yuasa H, Takakura N, Shimomura T, Suenobu S, Yamada T, Nagayama H, Oike Y, Suda T. | 01/21/2010 |
| Angiopoietin-1 is implicated in the maturation and remodeling of the vascular network during embryo development and in adult life through its tyrosine kinase receptor Tie-2 stimulates endothelial cells to migrate and change shape. | Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1.
Cascone I, Audero E, Giraudo E, Napione L, Maniero F, Philips MR, Collard JG, Serini G, Bussolino F. | 01/21/2010 |
| The autocrine/paracrine signaling of the Ang/Tie2 system is important for the up-regulated angiogenesis in the RA synovium, as well as for synoviocyte behavior, by regulating chemotactic cell movement. | Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis.
Takahara K, Iioka T, Furukawa K, Uchida T, Nakashima M, Tsukazaki T, Shindo H. | 01/21/2010 |
| sTie2 did not reduce goiter mass or vascular volume when used alone but was essential for complete goiter inhibition. | Complete inhibition of goiter in mice requires combined gene therapy modification of angiopoietin, vascular endothelial growth factor, and fibroblast growth factor signaling.
Ramsden JD, Buchanan MA, Egginton S, Watkinson JC, Mautner V, Eggo MC. | 01/21/2010 |
| sTie-2 increased significantly in the AMI patients; viability of HUVECs and tube formation area measured after stimulated with recombinant Tie-2/Fc chimera were observed to decrease, suggesting angiogenesis might be inhibited | Soluble angiopoietin receptor Tie-2 in patients with acute myocardial infarction and its effects on angiogenesis.
Wang C, Fu P, Li H, Gao R, Xiu R. | 01/21/2010 |
| expression of Ang-1 and Ang-2 is important for gastric tumor angiogenesis, and a possible autocrine/paracrine function of the angiopoietin/Tie2 system is involved in gastric cancer progression | Expression of angiopoietin 1, 2 and their common receptor Tie2 in human gastric carcinoma: implication for angiogenesis.
Moon WS, Park HS, Yu KH, Jang KY, Kang MJ, Park H, Tarnawski AS., Free PMC Article | 01/21/2010 |
| present study identifies ShcA as a mediator of the anti-apoptotic activity of venous malformation -mutant Tie2 | Mutant Tie2 causing venous malformation signals through Shc.
Morris PN, Dunmore BJ, Brindle NP. | 01/21/2010 |
| Tie2 was significantly overexpressed in leukemic blasts | Expression of angiopoietins and their receptor Tie2 in the bone marrow of patients with acute myeloid leukemia.
Schliemann C, Bieker R, Padro T, Kessler T, Hintelmann H, Buchner T, Berdel WE, Mesters RM. | 01/21/2010 |
| Circulating levels of Ang-2 and sTie-2 receptor were detectable but invariant in women during COS cycles. | Circulating levels of total angiopoietin-2 and the soluble Tie-2 receptor in women during ovarian stimulation and early gestation.
Molskness TA, Stouffer RL, Burry KA, Gorrill MJ, Lee DM, Patton PE. | 01/21/2010 |