| localized autocrine IGF-I activity might lead to increased permeability via changes in both the tight and adherens junction protein levels | Autocrine production of insulin-like growth factor-I (IGF-I) affects paracellular transport across epithelial cells in vitro.
Paye JM, Akers RM, Huckle WR, Forsten-Williams K. | 01/21/2010 |
| Food deprivation-induced decrease in circulating IGF-I in steers is associated with decrease in expression of different IGF-I mRNA variants and specific decrease in expression of growth hormone receptor mRNA variants 1C3 and 1A in liver. | Reduced serum insulin-like growth factor (IGF) I is associated with reduced liver IGF-I mRNA and liver growth hormone receptor mRNA in food-deprived cattle.
Wang Y, Eleswarapu S, Beal WE, Swecker WS Jr, Akers RM, Jiang H. | 01/21/2010 |
| Autokinase activity of IGF-IR in esophageal carcinoma cell line can be triggered by the exogenous addition of IGF-I. | Autocrine stimulation by insulin-like growth factor I is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells.
Liu YC, Leu CM, Wong FH, Fong WS, Chen SC, Chang C, Hu CP. | 01/21/2010 |
| GH dramatically inhibits the expression of IGFBP-5, and GH along with IGF-I enhanced the phosphorylation of Akt through the reduction of IGF binding protein (IGFBP)-5. | Growth hormone suppresses the expression of IGFBP-5, and promotes the IGF-I-induced phosphorylation of Akt in bovine mammary epithelial cells.
Sakamoto K, Yano T, Kobayashi T, Hagino A, Aso H, Obara Y. | 01/21/2010 |
| effects of insulin, IGF-I and IGF-II on apoptosis and cell proliferation in bovine blastocysts in vitro | Regulation of apoptosis in the bovine blastocyst by insulin and the insulin-like growth factor (IGF) superfamily.
Byrne AT, Southgate J, Brison DR, Leese HJ. | 01/21/2010 |
| allele and genotype frequencies of microsatellite markers located in the 5'-regulatory region of the IGF1 and GHR genes in beef cattle and effects of these markers on growth and carcass traits in an intensive production system | Effects of polymorphic microsatellites in the regulatory region of IGF1 and GHR on growth and carcass traits in beef cattle.
Curi RA, Oliveira HN, Silveira AC, Lopes CR. | 01/21/2010 |
| IGF1 has a role in chondrocyte biosynthesis in cartilage explants | Combined effects of dynamic tissue shear deformation and insulin-like growth factor I on chondrocyte biosynthesis in cartilage explants.
Jin M, Emkey GR, Siparsky P, Trippel SB, Grodzinsky AJ. | 01/21/2010 |
| Characterization of single nucleotide polymorphisms in IGF1 in relation to production traits. | Analysis of population differentiation in North Eurasian cattle (Bos taurus) using single nucleotide polymorphisms in three genes associated with production traits.
Li MH, Adamowicz T, Switonski M, Ammosov I, Ivanova Z, Kiselyova T, Popov R, Kantanen J. | 01/21/2010 |
| 3 haplotypes with an allele of igf1 showed significant associations with growth traits | Assessment of positional candidate genes myf5 and igf1 for growth on bovine chromosome 5 in commercial lines of Bos taurus.
Li C, Basarab J, Snelling WM, Benkel B, Murdoch B, Hansen C, Moore SS. | 01/21/2010 |
| Concentrations of IGF-I in fetal plasma, as determined by RIA, were significantly higher (P = 0.001) in nuclear transfer pregnancies | Insulin-like growth factor-I and binding proteins 1, 2, and 3 in bovine nuclear transfer pregnancies.
Ravelich SR, Breier BH, Reddy S, Keelan JA, Wells DN, Peterson AJ, Lee RS. | 01/21/2010 |
| Data show that 9-cis-retinoic acid enhanced midkine gene expression, but not insulin-like growth factor-I gene expression, in cumulus-granulosa cells. | 9-cis-retinoic acid during in vitro maturation improves development of the bovine oocyte and increases midkine but not IGF-I expression in cumulus-granulosa cells.
Gómez E, Royo LJ, Duque P, Carneiro G, Hidalgo C, Goyache F, Lorenzo PL, Alvarez I, Facal N, Díez C. | 01/21/2010 |
| postweaning serum IGF-I concentration is moderately to highly heritable and has small positive genetic, environmental, and phenotypic correlations with BW other than birth weight and with pre- and postweaning gain | Genetic parameter estimates for serum insulin-like growth factor I concentrations, and body weight and weight gains in Angus beef cattle divergently selected for serum insulin-like growth factor I concentration.
Davis ME, Simmen RC. | 01/21/2010 |
| Plasma IGF-1 level and night plasma melatonin tended (P = 0.10) to be negatively correlated in prepubertal heifers. Light intensities of 10 lx or less had no effect on plasma IGF-1. | Plasma melatonin and insulin-like growth factor-1 responses to dim light at night in dairy heifers.
Muthuramalingam P, Kennedy AD, Berry RJ. | 01/21/2010 |