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    AGR2 anterior gradient 2, protein disulphide isomerase family member [ Homo sapiens (human) ]

    Gene ID: 10551, updated on 6-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    AGR2 is expressed and secreted during pancreatic cancer development and plays an important role in cancer cell growth and survival.

    Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival.
    Ramachandran V, Arumugam T, Wang H, Logsdon CD., Free PMC Article

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (2) articles

    Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ.

    Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.
    Zheng W, Rosenstiel P, Huse K, Sina C, Valentonyte R, Mah N, Zeitlmann L, Grosse J, Ruf N, Nürnberg P, Costello CM, Onnie C, Mathew C, Platzer M, Schreiber S, Hampe J.

    03/13/2008
    Elevated levels of AGR2 are associated with the metastatic potential of breast cancer

    Physiological stress induces the metastasis marker AGR2 in breast cancer cells.
    Zweitzig DR, Smirnov DA, Connelly MC, Terstappen LW, O'Hara SM, Moran E.

    01/21/2010
    increased AGR2 expression is a valuable prognostic factor to predict the clinical outcome of the prostate cancer patients.

    Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients.
    Zhang Y, Forootan SS, Liu D, Barraclough R, Foster CS, Rudland PS, Ke Y.

    01/21/2010
    A prognostic effect of AGR2 for overall survival could be shown, which became independently significant for the group of nodal-negative tumors.

    Prognostic relevance of AGR2 expression in breast cancer.
    Fritzsche FR, Dahl E, Pahl S, Burkhardt M, Luo J, Mayordomo E, Gansukh T, Dankof A, Knuechel R, Denkert C, Winzer KJ, Dietel M, Kristiansen G.

    01/21/2010
    AGR2 may serve as a potential therapeutic target and/or molecular marker for prostate cancer.

    AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer.
    Zhang JS, Gong A, Cheville JC, Smith DI, Young CY.

    01/21/2010
    hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.

    hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.
    Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, Daviet L, Legrain P, Parekh R, Harris AL, Terrett JA., Free PMC Article

    01/21/2010
    specific induction of Hag2 and Hag3 during hormone-induced breast carcinomas further support developmental specificity for the PDI/ERp family members

    Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family.
    Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M.

    01/21/2010
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