| IP-10/CXCR3 signaling is associated with the pathogenesis of human myasthenia gravis. | Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis.
Feferman T, Maiti PK, Berrih-Aknin S, Bismuth J, Bidault J, Fuchs S, Souroujon MC. | 01/21/2010 |
| Pretransplant serum CXCL10 levels greater than 150 pg/mL confer an increased risk of early, severe, acute rejection. | High CXCL10 expression in rejected kidneys and predictive role of pretransplant serum CXCL10 for acute rejection and chronic allograft nephropathy.
Lazzeri E, Rotondi M, Mazzinghi B, Lasagni L, Buonamano A, Rosati A, Pradella F, Fossombroni V, La Villa G, Gacci M, Bertoni E, Serio M, Salvadori M, Romagnani P. | 01/21/2010 |
| Furthermore, hyaluronan, by inducing IL-8 and IP-10 by distinct pathways, provides a unique target for differential regulation of key inflammatory chemokines. | Differential regulation of hyaluronan-induced IL-8 and IP-10 in airway epithelial cells.
Boodoo S, Spannhake EW, Powell JD, Horton MR. | 01/21/2010 |
| Increased sCXCL10 is not associated with Hyper or Hypo per se, but is specifically sustained by the autoimmune inflammatory event occurring in both Graves disease and autoimmune thyroiditis | Increased serum CXCL10 in Graves' disease or autoimmune thyroiditis is not associated with hyper- or hypothyroidism per se, but is specifically sustained by the autoimmune, inflammatory process.
Antonelli A, Fallahi P, Rotondi M, Ferrari SM, Romagnani P, Grosso M, Ferrannini E, Serio M. | 01/21/2010 |
| Elevated systemic levels of the chemokines MCP-1, IL-8, and IP-10 precede coronary heart disease but do not represent independent risk factors. | Chemokines and incident coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.
Herder C, Baumert J, Thorand B, Martin S, Löwel H, Kolb H, Koenig W. | 01/21/2010 |
| M. bovis BCG-infected human epithelial cells can have an active role in a local inflammatory immune response via the secretion of IL-4, CXCL-8 and CXCL-10, which can be selectively regulated by Th2-derived cytokines | Expression and secretion of CXCL-8 and CXCL-10 from mycobacterium bovis BCG-infected human epithelial cells: role of IL-4.
Méndez-Samperio P, Miranda E, Vázquez A., Free PMC Article | 01/21/2010 |
| The early induction of IP-10 and IL-2, as well as the subsequent over-production of IL-6 and lack of IL-10 production, probably contribute to the main immuno-pathological processes involved in lung injury in SARS. | Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome.
Chien JY, Hsueh PR, Cheng WC, Yu CJ, Yang PC., Free PMC Article | 01/21/2010 |
| IP-10 may play an important role in regulating lymphocytes into the lung and ENA-78 may be associated with lung parenchymal disease in pulmonary sarcoidosis. | Elevated levels of interferon gamma-inducible protein-10 and epithelial neutrophil-activating peptide-78 in patients with pulmonary sarcoidosis.
Sugiyama K, Mukae H, Ishii H, Kakugawa T, Ishimoto H, Nakayama S, Shirai R, Fujii T, Mizuta Y, Kohno S. | 01/21/2010 |
| bacterium-induced CXCL10(IP-10) secretion by osteoblast can be mediated in part through toll-like receptor 4 | Bacterium-induced CXCL10 secretion by osteoblasts can be mediated in part through toll-like receptor 4.
Gasper NA, Petty CC, Schrum LW, Marriott I, Bost KL., Free PMC Article | 01/21/2010 |
| IP-10 expression and secretion in human monocytic cells is selectively induced by leptin | IP-10, but not RANTES, is upregulated by leptin in monocytic cells.
Meier CA, Chicheportiche R, Dreyer M, Dayer JM. | 01/21/2010 |
| This chemokine receptor stimulates HIV-1 replication. | The C-X-C chemokine IP-10 stimulates HIV-1 replication.
Lane BR, King SR, Bock PJ, Strieter RM, Coffey MJ, Markovitz DM. | 01/21/2010 |
| The structure of IP-10 has been solved by NMR spectroscopy and the surface of IP-10 that interacts with the N-terminus of the receptor CXCR3 has been defined. | The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions.
Booth V, Keizer DW, Kamphuis MB, Clark-Lewis I, Sykes BD. | 01/21/2010 |
| High levels of CXCL10 are present in synovial fluid of children with juvenile idiopathic arthritis. | Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells.
Pharoah DS, Varsani H, Tatham RW, Newton KR, de Jager W, Prakken BJ, Klein N, Wedderburn LR., Free PMC Article | 01/21/2010 |
| CXCL10 is up-regulated in bronchoalveolar lavage fluid taken from human lungs 24 h after lung transplantation. | CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function.
Medoff BD, Wain JC, Seung E, Jackobek R, Means TK, Ginns LC, Farber JM, Luster AD. | 01/21/2010 |
| inhibitory effect of CXCL10/IP-10 on the binding of dengue virus to cells may represent a novel contribution of this chemokine to the host defense against viral infection | Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate.
Chen JP, Lu HL, Lai SL, Campanella GS, Sung JM, Lu MY, Wu-Hsieh BA, Lin YL, Lane TE, Luster AD, Liao F. | 01/21/2010 |
| IP-10 levels significantly reverse-correlated with vascular endothelial growth factor (VEGF) levels in uterine cervical cancers. | Expression of IP-10 related to angiogenesis in uterine cervical cancers.
Sato E, Fujimoto J, Toyoki H, Sakaguchi H, Alam SM, Jahan I, Tamaya T., Free PMC Article | 01/21/2010 |
| In a mouse model, this protein is expressed as a marker of hepatic inflammation and injury, suggesting a role in liver repair and regeneration. | Cytokine-responsive gene-2/IFN-inducible protein-10 expression in multiple models of liver and bile duct injury suggests a role in tissue regeneration.
Koniaris LG, Zimmers-Koniaris T, Hsiao EC, Chavin K, Sitzmann JV, Farber JM. | 09/24/2001 |