| DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility. | DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility.
Li G, Meng H, Bai Y, Wei W, Feng Y, Li M, Li H, He M, Zhang X, Wei S, Li Y, Guo H., Free PMC Article | 12/18/2021 |
| SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation. | SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
Bidault G, Virtue S, Petkevicius K, Jolin HE, Dugourd A, Guénantin AC, Leggat J, Mahler-Araujo B, Lam BYH, Ma MK, Dale M, Carobbio S, Kaser A, Fallon PG, Saez-Rodriguez J, McKenzie ANJ, Vidal-Puig A., Free PMC Article | 12/4/2021 |
| SREBP-1c and lipogenesis in the liver: an update1. | SREBP-1c and lipogenesis in the liver: an update1.
Ferré P, Phan F, Foufelle F. | 11/27/2021 |
| Autophagy activation and SREBP-1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells. | Autophagy activation and SREBP-1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells.
Pham DV, Tilija Pun N, Park PH., Free PMC Article | 11/27/2021 |
| SREBP1-Induced Glutamine Synthetase Triggers a Feedforward Loop to Upregulate SREBP1 through Sp1 O-GlcNAcylation and Augments Lipid Droplet Formation in Cancer Cells. | SREBP1-Induced Glutamine Synthetase Triggers a Feedforward Loop to Upregulate SREBP1 through Sp1 O-GlcNAcylation and Augments Lipid Droplet Formation in Cancer Cells.
Jhu JW, Yan JB, Lin ZH, Lin SC, Peng IC., Free PMC Article | 10/23/2021 |
| The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy. | The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy.
Yang B, Zhang B, Cao Z, Xu X, Huo Z, Zhang P, Xiang S, Zhao Z, Lv C, Meng M, Zhang G, Dong L, Shi S, Yang L, Zhou Q., Free PMC Article | 09/25/2021 |
| An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth. | An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth.
Liu L, Yan H, Ruan M, Yang H, Wang L, Lei B, Sun X, Chang C, Huang G, Xie W., Free PMC Article | 08/21/2021 |
| Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer. | Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.
Li LY, Yang Q, Jiang YY, Yang W, Jiang Y, Li X, Hazawa M, Zhou B, Huang GW, Xu XE, Gery S, Zhang Y, Ding LW, Ho AS, Zumsteg ZS, Wang MR, Fullwood MJ, Freedland SJ, Meltzer SJ, Xu LY, Li EM, Koeffler HP, Lin DC., Free PMC Article | 08/7/2021 |
| ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway. | ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway.
Chen J, Ding C, Chen Y, Hu W, Yu C, Peng C, Feng X, Cheng Q, Wu W, Lu Y, Xie H, Zhou L, Wu J, Zheng S. | 08/7/2021 |
| LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling. | LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling.
Guo S, Zhang Y, Wang S, Yang T, Ma B, Li X, Zhang Y, Jiang X. | 07/10/2021 |
| Exome sequencing identifies a SREBF1 recurrent ARG557CYS mutation as the cause of hereditary mucoepithelial dysplasia in a family with high clinical variability. | Exome sequencing identifies a SREBF1 recurrent ARG557CYS mutation as the cause of hereditary mucoepithelial dysplasia in a family with high clinical variability.
Chacon-Camacho OF, Arce-Gonzalez R, Ordaz-Robles T, Perezpeña-Diazconti M, Nava-Castañeda A, Zenteno JC. | 06/26/2021 |
| Association of phosphoenolpyruvate carboxykinase 1 protein kinase activity-dependent sterol regulatory element-binding protein 1 activation with prognosis of oesophageal carcinoma. | Association of phosphoenolpyruvate carboxykinase 1 protein kinase activity-dependent sterol regulatory element-binding protein 1 activation with prognosis of oesophageal carcinoma.
Shao F, Bian X, Jiang H, Zhao G, Zhu L, Xu D, Wang S, Guo W, Xing D, Xue Q, Gao Y, He J, Lu Z. | 06/26/2021 |
| Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPalpha/SREBP-1 pathway. | Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Pang B, Zhang J, Zhang X, Yuan J, Shi Y, Qiao L. | 06/12/2021 |
| Srebf1 Controls Midbrain Dopaminergic Neurogenesis. | Srebf1 Controls Midbrain Dopaminergic Neurogenesis.
Toledo EM, Yang S, Gyllborg D, van Wijk KE, Sinha I, Varas-Godoy M, Grigsby CL, Lönnerberg P, Islam S, Steffensen KR, Linnarsson S, Arenas E. | 06/5/2021 |
| Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95. | Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95.
Shin HS, Lee Y, Shin MH, Cho SI, Zouboulis CC, Kim MK, Lee DH, Chung JH., Free PMC Article | 05/29/2021 |
| UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes. | UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes.
Tian YD, Chung MH, Quan QL, Lee DH, Kim EJ, Chung JH., Free PMC Article | 05/29/2021 |
| mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis. | mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Triki M, Rinaldi G, Planque M, Broekaert D, Winkelkotte AM, Maier CR, Janaki Raman S, Vandekeere A, Van Elsen J, Orth MF, Grünewald TGP, Schulze A, Fendt SM., Free PMC Article | 05/1/2021 |
| UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis. | UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis.
Heo MJ, Kang SH, Kim YS, Lee JM, Yu J, Kim HR, Lim H, Kim KM, Jung J, Jeong LS, Moon A, Kim SG. | 04/24/2021 |
| The active nuclear form of SREBP1 amplifies ER stress and autophagy via regulation of PERK. | The active nuclear form of SREBP1 amplifies ER stress and autophagy via regulation of PERK.
Hu Q, Mao Y, Liu M, Luo R, Jiang R, Guo F. | 04/24/2021 |
| SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC. | SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC.
Ruiz CF, Montal ED, Haley JA, Bott AJ, Haley JD., Free PMC Article | 03/6/2021 |
| Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer. | Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer.
Sun Q, Yu X, Peng C, Liu N, Chen W, Xu H, Wei H, Fang K, Dong Z, Fu C, Xu Y, Lu W. | 03/6/2021 |
| Visfatin and SREBP-1c mRNA Expressions and Serum Levels Among Egyptian Women with Polycystic Ovary Syndrome. | Visfatin and SREBP-1c mRNA Expressions and Serum Levels Among Egyptian Women with Polycystic Ovary Syndrome.
Abdul-Maksoud RS, Zidan HE, Saleh HS, Amer SA. | 02/27/2021 |
| Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis. | Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis.
Yi J, Zhu J, Wu J, Thompson CB, Jiang X., Free PMC Article | 02/2/2021 |
| Hereditary Mucoepithelial Dysplasia Results from Heterozygous Variants at p.Arg557 Mutational Hotspot in SREBF1, Encoding a Transcription Factor Involved in Cholesterol Homeostasis. | Hereditary Mucoepithelial Dysplasia Results from Heterozygous Variants at p.Arg557 Mutational Hotspot in SREBF1, Encoding a Transcription Factor Involved in Cholesterol Homeostasis.
Morice-Picard F, Michaud V, Lasseaux E, Rezvani HR, Plaisant C, Bessis D, Leauté-Labrèze C, Arveiler B, Taieb A, Trimouille A, Boralevi F. | 01/9/2021 |
| SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. | SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait.
Wu S, Näär AM., Free PMC Article | 10/31/2020 |