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    Slc34a1 solute carrier family 34 (sodium phosphate), member 1 [ Mus musculus (house mouse) ]

    Gene ID: 20505, updated on 16-Oct-2021

    Summary

    Official Symbol
    Slc34a1provided by MGI
    Official Full Name
    solute carrier family 34 (sodium phosphate), member 1provided by MGI
    Primary source
    MGI:MGI:1345284
    See related
    Ensembl:ENSMUSG00000021490
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Npt2; Npt2a; Slc17a2; NaPi-IIa
    Expression
    Restricted expression toward kidney adult (RPKM 2731.8) See more
    Orthologs
    NEW
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    Genomic context

    See Slc34a1 in Genome Data Viewer
    Location:
    13 B1; 13 29.81 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55547435..55562508)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55399622..55414695)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (55501009..55516056)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene lectin, mannose-binding 2 Neighboring gene regulator of G-protein signaling 14 Neighboring gene profilin 3 Neighboring gene coagulation factor XII (Hageman factor) Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene microRNA 6943

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sodium:phosphate symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sodium:phosphate symporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in arsenate ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within bone remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular phosphate ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphate ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphate ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphate ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phosphate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of sodium-dependent phosphate transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to cadmium ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to lead ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to mercury ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium ion import across plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sodium-dependent phosphate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in brush border IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in brush border membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intrinsic component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    sodium-dependent phosphate transport protein 2A
    Names
    Na(+)-dependent phosphate cotransporter 2A
    Na(+)/Pi cotransporter 2A
    Na+-phosphate cotransporter type II
    Na/Pi cotransporter
    naPi-2a
    naPi-7
    renal Na+/Pi transporter
    sodium-phosphate transport protein 2A
    sodium/phosphate cotransporter 2A
    solute carrier family 17 (sodium/hydrogen exchanger), member 2
    solute carrier family 34 member 1
    type IIa Na+/Pi-cotransporter

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011392.2NP_035522.2  sodium-dependent phosphate transport protein 2A

      See identical proteins and their annotated locations for NP_035522.2

      Status: VALIDATED

      Source sequence(s)
      AB163922, CB952922, CT009762
      Consensus CDS
      CCDS49271.1
      UniProtKB/TrEMBL
      Q9D2V6
      Related
      ENSMUSP00000059138.8, ENSMUST00000057167.9
      Conserved Domains (2) summary
      TIGR01013
      Location:108588
      2a58; Phosphate:Na+ Symporter (PNaS) Family
      pfam02690
      Location:113204
      Na_Pi_cotrans; Na+/Pi-cotransporter

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      55547435..55562508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517177.3XP_006517240.1  sodium-dependent phosphate transport protein 2A isoform X1

      Conserved Domains (1) summary
      TIGR01013
      Location:87497
      2a58; Phosphate:Na+ Symporter (PNaS) Family
    2. XM_006517178.3XP_006517241.1  sodium-dependent phosphate transport protein 2A isoform X2

      Conserved Domains (1) summary
      TIGR01013
      Location:1400
      2a58; Phosphate:Na+ Symporter (PNaS) Family
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