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    Vsig4 V-set and immunoglobulin domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 278180, updated on 5-Jan-2022

    Summary

    Official Symbol
    Vsig4provided by MGI
    Official Full Name
    V-set and immunoglobulin domain containing 4provided by MGI
    Primary source
    MGI:MGI:2679720
    See related
    Ensembl:ENSMUSG00000044206
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CRIg; Z39IG; BC025105; A530061A11
    Summary
    Predicted to enable complement component C3b binding activity. Acts upstream of or within negative regulation of T cell proliferation and negative regulation of interleukin-2 production. Predicted to be part of protein-containing complex. Is expressed in bone marrow; oviduct; and thyroid gland. Orthologous to human VSIG4 (V-set and immunoglobulin domain containing 4). [provided by Alliance of Genome Resources, Nov 2021]
    Expression
    Biased expression in liver E18 (RPKM 5.0), liver adult (RPKM 2.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Vsig4 in Genome Data Viewer
    Location:
    X; X C3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (95290807..95337044, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (96247201..96293438, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (93442542..93488777, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA F630028O10 gene Neighboring gene solute carrier family 37 (glycerol-3-phosphate transporter), member 3 pseudogene Neighboring gene microRNA 223 Neighboring gene predicted gene, 18171 Neighboring gene heat shock transcription factor 3 Neighboring gene cofilin 1, non-muscle pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Clone Names

    • MGC36211

    General protein information

    Preferred Names
    V-set and immunoglobulin domain-containing protein 4
    Names
    complement receptor of the immunoglobulin superfamily

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177789.5NP_808457.1  V-set and immunoglobulin domain-containing protein 4 precursor

      See identical proteins and their annotated locations for NP_808457.1

      Status: VALIDATED

      Source sequence(s)
      AL831708
      Consensus CDS
      CCDS30288.1
      UniProtKB/TrEMBL
      F6TUL9
      Related
      ENSMUSP00000051521.2, ENSMUST00000050707.3
      Conserved Domains (1) summary
      cl11960
      Location:35136
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      95290807..95337044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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