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    Fbxo16 F-box protein 16 [ Mus musculus (house mouse) ]

    Gene ID: 50759, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fbxo16provided by MGI
    Official Full Name
    F-box protein 16provided by MGI
    Primary source
    MGI:MGI:1354706
    See related
    Ensembl:ENSMUSG00000034532 AllianceGenome:MGI:1354706
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fbx16; 4932435C24Rik
    Summary
    Orthologous to human FBXO16 (F-box protein 16). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E14 (RPKM 1.8), whole brain E14.5 (RPKM 1.7) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    14 D1; 14 34.19 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65504067..65561422)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65266618..65323973)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene frizzled class receptor 3 Neighboring gene predicted gene 9086 Neighboring gene predicted gene, 52141 Neighboring gene STARR-seq mESC enhancer starr_36966 Neighboring gene STARR-seq mESC enhancer starr_36967 Neighboring gene predicted gene, 41178 Neighboring gene STARR-positive B cell enhancer ABC_E4114 Neighboring gene STARR-positive B cell enhancer ABC_E3120 Neighboring gene predicted gene, 48449 Neighboring gene zinc finger protein 395 Neighboring gene STARR-seq mESC enhancer starr_36972 Neighboring gene STARR-positive B cell enhancer mm9_chr14:66008600-66008901 Neighboring gene prepronociceptin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A family of mammalian F-box proteins. Winston JT, et al. Curr Biol, 1999 Oct 21. PMID 10531037
    2. Systematic analysis and nomenclature of mammalian F-box proteins. Jin J, et al. Genes Dev, 2004 Nov 1. PMID 15520277, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC144594

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360381.1 → NP_001347310.1  F-box only protein 16 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK164657, BC086690
      UniProtKB/TrEMBL
      Q8BRT0

    2. NM_001360383.1 → NP_001347312.1  F-box only protein 16 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK164657, BC086690
      Consensus CDS
      CCDS88689.1
      UniProtKB/TrEMBL
      Q0VGS0, Q8BRT0
      Related
      ENSMUSP00000153094.2, ENSMUST00000226005.2
      Conserved Domains (1) summary
      pfam12937
      Location:92 → 129
      F-box-like; F-box-like

    3. NM_015795.2 → NP_056610.1  F-box only protein 16 isoform 1

      See identical proteins and their annotated locations for NP_056610.1

      Status: VALIDATED

      Source sequence(s)
      AK164657, BC086690
      Consensus CDS
      CCDS36956.1
      UniProtKB/Swiss-Prot
      Q3TP74, Q8C5V6, Q9QZM9
      UniProtKB/TrEMBL
      Q14BG9, Q8BRT0
      Related
      ENSMUSP00000153015.2, ENSMUST00000224629.2
      Conserved Domains (1) summary
      pfam12937
      Location:92 → 135
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      65504067..65561422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QZM9.1 GenPept UniProtKB/Swiss-Prot:Q9QZM9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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