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    Baat bile acid-Coenzyme A: amino acid N-acyltransferase [ Mus musculus (house mouse) ]

    Gene ID: 12012, updated on 23-Jun-2021

    Summary

    Official Symbol
    Baatprovided by MGI
    Official Full Name
    bile acid-Coenzyme A: amino acid N-acyltransferaseprovided by MGI
    Primary source
    MGI:MGI:106642
    See related
    Ensembl:ENSMUSG00000039653
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BA; BAT; AI118337; AI158864
    Expression
    Biased expression in liver adult (RPKM 17.8), liver E18 (RPKM 3.3) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Baat in Genome Data Viewer
    Location:
    4 B1; 4 26.51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (49489416..49507915, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (49489416..49507915, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (49502290..49519430, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene acyl-coenzyme A amino acid N-acyltransferase 1 Neighboring gene predicted gene, 26424 Neighboring gene predicted gene, 33009 Neighboring gene predicted gene, 32894 Neighboring gene predicted gene, 52736 Neighboring gene mitochondrial ribosomal protein L50

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables N-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables choloyl-CoA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycine N-choloyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables long-chain acyl-CoA hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables medium-chain acyl-CoA hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables myristoyl-CoA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables palmitoyl-CoA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables very long chain acyl-CoA hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in acyl-CoA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bile acid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bile acid conjugation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within bile acid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in glycine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in taurine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    bile acid-CoA:amino acid N-acyltransferase
    Names
    BACAT
    bile acid-CoA thioesterase
    bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase
    choloyl-CoA hydrolase
    glycine N-choloyltransferase
    long-chain fatty-acyl-CoA hydrolase
    taurine N-acyltransferase
    NP_031545.2
    XP_006537628.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007519.3NP_031545.2  bile acid-CoA:amino acid N-acyltransferase

      See identical proteins and their annotated locations for NP_031545.2

      Status: VALIDATED

      Source sequence(s)
      AA255212, AK017923, BB800891, BY080271, CB947692, U95215
      Consensus CDS
      CCDS18173.1
      UniProtKB/Swiss-Prot
      Q91X34
      Related
      ENSMUSP00000041983.3, ENSMUST00000043056.9
      Conserved Domains (2) summary
      pfam08840
      Location:207414
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
      pfam04775
      Location:14140
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      49489416..49507915 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537565.4XP_006537628.1  bile acid-CoA:amino acid N-acyltransferase isoform X1

      Conserved Domains (1) summary
      pfam08840
      Location:34241
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
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