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    Mfsd4b1 major facilitator superfamily domain containing 4B1 [ Mus musculus (house mouse) ]

    Gene ID: 215929, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mfsd4b1provided by MGI
    Official Full Name
    major facilitator superfamily domain containing 4B1provided by MGI
    Primary source
    MGI:MGI:2143575
    See related
    Ensembl:ENSMUSG00000038522
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI3173; Naglt1a; AI317395; AI482555
    Expression
    Biased expression in kidney adult (RPKM 31.8), liver adult (RPKM 11.3) and 1 other tissue See more
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    Genomic context

    See Mfsd4b1 in Genome Data Viewer
    Location:
    10; 10 B1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (39877569..39901264, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40001573..40025268, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (39721379..39745074, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 4B3, pseudogene Neighboring gene neutrophil immunoglobulin-like receptor 1 Neighboring gene major facilitator superfamily domain containing 4B5 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene solute carrier family 16 (monocarboxylic acid transporters), member 10 Neighboring gene predicted gene, 25613 Neighboring gene predicted gene, 31992

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC25869

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sodium-dependent glucose transporter 1A
    Names
    major facilitator superfamily domain-containing protein 4B1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144821.4NP_659070.2  sodium-dependent glucose transporter 1A

      See identical proteins and their annotated locations for NP_659070.2

      Status: VALIDATED

      Source sequence(s)
      AC168279
      Consensus CDS
      CCDS35884.2
      UniProtKB/Swiss-Prot
      Q8VCV9
      Related
      ENSMUSP00000128324.3, ENSMUST00000163705.3
      Conserved Domains (2) summary
      cd06174
      Location:1404
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      PRK03699
      Location:12422
      PRK03699; putative transporter; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      39877569..39901264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512696.5XP_006512759.1  sodium-dependent glucose transporter 1A isoform X1

      Conserved Domains (1) summary
      cl28910
      Location:1339
      MFS; Major Facilitator Superfamily
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