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    Scara5 scavenger receptor class A, member 5 [ Mus musculus (house mouse) ]

    Gene ID: 71145, updated on 23-Jun-2021

    Summary

    Official Symbol
    Scara5provided by MGI
    Official Full Name
    scavenger receptor class A, member 5provided by MGI
    Primary source
    MGI:MGI:1918395
    See related
    Ensembl:ENSMUSG00000022032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tesr; AV278087; 4932433F15Rik; 4933425F03Rik
    Expression
    Biased expression in bladder adult (RPKM 37.1), mammary gland adult (RPKM 14.4) and 10 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Scara5 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65903852..66002275)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65666403..65764826)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66285240..66383663)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene nuclear GTPase, germinal center associated Neighboring gene predicted gene, 30245 Neighboring gene predicted gene, 53863 Neighboring gene PDZ binding kinase Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ferritin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular iron ion homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within cellular response to heat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in iron ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein homotrimerization IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endocytic vesicle membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    scavenger receptor class A member 5
    Names
    scavenger receptor class A, member 5 (putative)
    testis expressed scavenger receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168318.1NP_001161790.1  scavenger receptor class A member 5 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two 3' exons but has an alternate 3' exon, as compared to variant 1. The resulting isoform (2) is shorter and has a different C-terminus, as compared to isoform 1.
      Source sequence(s)
      AK016543, AK033154, BY791906
      Consensus CDS
      CCDS49523.1
      UniProtKB/Swiss-Prot
      Q8K299
      Related
      ENSMUSP00000063391.7, ENSMUST00000069226.7
      Conserved Domains (2) summary
      pfam01391
      Location:306373
      Collagen; Collagen triple helix repeat (20 copies)
      pfam08496
      Location:67115
      Peptidase_S49_N; Peptidase family S49 N-terminal
    2. NM_028903.2NP_083179.2  scavenger receptor class A member 5 isoform 1

      See identical proteins and their annotated locations for NP_083179.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK133176, BC016096
      Consensus CDS
      CCDS27214.1
      UniProtKB/Swiss-Prot
      Q8K299
      Related
      ENSMUSP00000022610.9, ENSMUST00000022610.15
      Conserved Domains (3) summary
      PRK09039
      Location:55249
      PRK09039; peptidoglycan -binding protein
      smart00202
      Location:389489
      SR; Scavenger receptor Cys-rich
      pfam01391
      Location:318373
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      65903852..66002275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158851.1XP_036014744.1  scavenger receptor class A member 5 isoform X1

      Conserved Domains (3) summary
      PRK09039
      Location:55249
      PRK09039; peptidoglycan -binding protein
      smart00202
      Location:389489
      SR; Scavenger receptor Cys-rich
      pfam01391
      Location:318373
      Collagen; Collagen triple helix repeat (20 copies)
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