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    Golga2 golgi autoantigen, golgin subfamily a, 2 [ Mus musculus (house mouse) ]

    Gene ID: 99412, updated on 23-Jun-2021

    Summary

    Official Symbol
    Golga2provided by MGI
    Official Full Name
    golgi autoantigen, golgin subfamily a, 2provided by MGI
    Primary source
    MGI:MGI:2139395
    See related
    Ensembl:ENSMUSG00000002546
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GM130; AW555139
    Expression
    Ubiquitous expression in ovary adult (RPKM 20.8), limb E14.5 (RPKM 16.9) and 28 other tissues See more
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    Genomic context

    See Golga2 in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (32178299..32197925)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (32288287..32307913)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (32143773..32163441)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L36 pseudogene Neighboring gene SWI5 recombination repair homolog (yeast) Neighboring gene dynamin 1 Neighboring gene microRNA 3154 Neighboring gene microRNA 199b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA4150

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables importin-alpha family protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables importin-alpha family protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables syntaxin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within Golgi localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in asymmetric cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in meiotic spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein homotetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in COPII-coated ER to Golgi transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in Golgi cis cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi cis cisterna ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi cisterna membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi cisterna membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cis-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cis-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    golgin subfamily A member 2
    Names
    130 kDa cis-Golgi matrix protein
    SY11 protein
    golgin-95

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080968.2NP_001074437.2  golgin subfamily A member 2 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Consensus CDS
      CCDS38101.1
      Related
      ENSMUSP00000159316.2, ENSMUST00000239447.2
      Conserved Domains (2) summary
      TIGR02168
      Location:136467
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15070
      Location:369987
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    2. NM_001362695.2NP_001349624.2  golgin subfamily A member 2 isoform c

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Conserved Domains (2) summary
      COG1196
      Location:194541
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15070
      Location:369987
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    3. NM_001362696.2NP_001349625.2  golgin subfamily A member 2 isoform d

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Conserved Domains (2) summary
      COG1196
      Location:167514
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15070
      Location:342960
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    4. NM_001362697.2NP_001349626.2  golgin subfamily A member 2 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Related
      ENSMUSP00000080374.9, ENSMUST00000081670.14
      Conserved Domains (2) summary
      TIGR02168
      Location:104435
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15070
      Location:337955
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    5. NM_001362698.2NP_001349627.2  golgin subfamily A member 2 isoform f

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Conserved Domains (2) summary
      COG1196
      Location:135482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15070
      Location:310928
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    6. NM_133852.3NP_598613.3  golgin subfamily A member 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL808027
      Consensus CDS
      CCDS38100.1
      Related
      ENSMUSP00000097768.4, ENSMUST00000100194.10
      Conserved Domains (2) summary
      TIGR02168
      Location:163494
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15070
      Location:3961014
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      32178299..32197925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498491.4XP_006498554.1  golgin subfamily A member 2 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:193540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15070
      Location:368986
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    2. XM_017319359.2XP_017174848.1  golgin subfamily A member 2 isoform X1

      Conserved Domains (2) summary
      TIGR02168
      Location:143474
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15070
      Location:376994
      GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
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