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    Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 [ Mus musculus (house mouse) ]

    Gene ID: 71988, updated on 5-Sep-2021

    Summary

    Official Symbol
    Esco2provided by MGI
    Official Full Name
    establishment of sister chromatid cohesion N-acetyltransferase 2provided by MGI
    Primary source
    MGI:MGI:1919238
    See related
    Ensembl:ENSMUSG00000022034
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410004I17Rik; D030072L07Rik
    Expression
    Biased expression in liver E14 (RPKM 10.1), liver E14.5 (RPKM 7.6) and 10 other tissues See more
    Orthologs
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    Genomic context

    See Esco2 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66056476..66071418, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65819027..65833969, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66437864..66452806, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene scavenger receptor class A, member 5 Neighboring gene PDZ binding kinase Neighboring gene coiled-coil domain containing 25 Neighboring gene predicted gene, 41181

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in XY body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromocenter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    N-acetyltransferase ESCO2
    Names
    ECO1 homolog 2
    establishment of cohesion 1 homolog 2
    NP_082315.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028039.2NP_082315.3  N-acetyltransferase ESCO2

      See identical proteins and their annotated locations for NP_082315.3

      Status: VALIDATED

      Source sequence(s)
      AA189671, AA881675, AK010391, AV216701, BY029949, CF168369, CF730483
      Consensus CDS
      CCDS27216.1
      UniProtKB/Swiss-Prot
      Q8CIB9
      Related
      ENSMUSP00000022613.10, ENSMUST00000022613.10
      Conserved Domains (2) summary
      pfam13878
      Location:371410
      zf-C2H2_3; zinc-finger of acetyl-transferase ESCO
      pfam13880
      Location:520582
      Acetyltransf_13; ESCO1/2 acetyl-transferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      66056476..66071418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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