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    Eaf2 ELL associated factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 106389, updated on 23-Jun-2021

    Summary

    Official Symbol
    Eaf2provided by MGI
    Official Full Name
    ELL associated factor 2provided by MGI
    Primary source
    MGI:MGI:2146616
    See related
    Ensembl:ENSMUSG00000022838
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tr; Fes; U19; FEST; Festa; Traits; FESTA-L; FESTA-S; AW048865
    Expression
    Broad expression in bladder adult (RPKM 1.1), kidney adult (RPKM 1.0) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Eaf2 in Genome Data Viewer
    Location:
    16; 16 B3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (36613246..36695275, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (36792884..36875068, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (36792970..36874912, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene RNA guanylyltransferase and 5'-phosphatase pseudogene Neighboring gene solute carrier family 15 (H+/peptide transporter), member 2 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene IQ calmodulin-binding motif containing 1 Neighboring gene RIKEN cDNA 4930565N06 gene Neighboring gene golgi autoantigen, golgin subfamily b, macrogolgin 1 Neighboring gene hematopoietic cell specific Lyn substrate 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription elongation regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription elongation regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of super elongation complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription elongation factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription elongation factor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ELL-associated factor 2
    Names
    ehrlich S-II transcriptional activator factor
    testosterone regulated apoptosis inducer and tumor suppressor
    testosterone-regulated apoptosis inducer and tumor suppressor protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113401.1NP_001106872.1  ELL-associated factor 2 isoform b

      See identical proteins and their annotated locations for NP_001106872.1

      Status: VALIDATED

      Source sequence(s)
      AC117662, AY034479, BG144504
      Consensus CDS
      CCDS49843.1
      UniProtKB/Swiss-Prot
      Q91ZD6
      Related
      ENSMUSP00000110477.3, ENSMUST00000114829.9
      Conserved Domains (1) summary
      pfam09816
      Location:17113
      EAF; RNA polymerase II transcription elongation factor
    2. NM_001113405.1NP_001106876.1  ELL-associated factor 2 isoform a

      See identical proteins and their annotated locations for NP_001106876.1

      Status: VALIDATED

      Source sequence(s)
      AB081298, AC117662, AY049021
      Consensus CDS
      CCDS37335.1
      UniProtKB/Swiss-Prot
      Q91ZD6
      Related
      ENSMUSP00000110473.2, ENSMUST00000114825.3
    3. NM_001358102.1NP_001345031.1  ELL-associated factor 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC117662, AC154232
      Consensus CDS
      CCDS37335.1
    4. NM_134111.2NP_598872.1  ELL-associated factor 2 isoform a

      See identical proteins and their annotated locations for NP_598872.1

      Status: VALIDATED

      Source sequence(s)
      BC056626
      Consensus CDS
      CCDS37335.1
      UniProtKB/Swiss-Prot
      Q91ZD6
      Related
      ENSMUSP00000075331.6, ENSMUST00000075946.12

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      36613246..36695275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521685.5XP_006521748.1  ELL-associated factor 2 isoform X3

      See identical proteins and their annotated locations for XP_006521748.1

      UniProtKB/Swiss-Prot
      Q91ZD6
    2. XM_036159730.1XP_036015623.1  ELL-associated factor 2 isoform X3

    3. XM_006521682.4XP_006521745.1  ELL-associated factor 2 isoform X1

      See identical proteins and their annotated locations for XP_006521745.1

      UniProtKB/TrEMBL
      K4DI60
      Related
      ENSMUSP00000023537.6, ENSMUST00000023537.6
      Conserved Domains (1) summary
      pfam09816
      Location:17115
      EAF; RNA polymerase II transcription elongation factor
    4. XM_036159731.1XP_036015624.1  ELL-associated factor 2 isoform X3

    5. XM_006521683.1XP_006521746.1  ELL-associated factor 2 isoform X3

      See identical proteins and their annotated locations for XP_006521746.1

      UniProtKB/Swiss-Prot
      Q91ZD6
    6. XM_011245800.3XP_011244102.1  ELL-associated factor 2 isoform X2

      See identical proteins and their annotated locations for XP_011244102.1

      Conserved Domains (1) summary
      pfam09816
      Location:17115
      EAF; RNA polymerase II transcription elongation factor

    RNA

    1. XR_003951743.2 RNA Sequence

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