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    Adgrg5 adhesion G protein-coupled receptor G5 [ Mus musculus (house mouse) ]

    Gene ID: 382045, updated on 23-Jun-2021

    Summary

    Official Symbol
    Adgrg5provided by MGI
    Official Full Name
    adhesion G protein-coupled receptor G5provided by MGI
    Primary source
    MGI:MGI:2685955
    See related
    Ensembl:ENSMUSG00000061577
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PGR; Gpr1; PGR27; Gm1109; Gpr114
    Expression
    Biased expression in spleen adult (RPKM 15.2), thymus adult (RPKM 10.3) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Adgrg5 in Genome Data Viewer
    Location:
    8; 8 C5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (95648439..95669921)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (94921811..94943293)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (97447594..97467190)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) II (DNA directed) polypeptide C Neighboring gene docking protein 4 Neighboring gene coiled-coil domain containing 102A Neighboring gene predicted gene, 30968 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene predicted gene, 51544 Neighboring gene adhesion G protein-coupled receptor G3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    adhesion G-protein coupled receptor G5
    Names
    G protein coupled receptor Gpr114
    G protein-coupled receptor 114
    G-protein coupled receptor PGR27
    probable G-protein coupled receptor 114

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033468.3NP_001028640.2  adhesion G-protein coupled receptor G5 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001028640.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has two alternate splice sites in the 5' UTR and CDS respectively, as compared to variant 1. The resulting isoform (2) lacks an internal amino acid, as compared to isoform 1.
      Source sequence(s)
      AK028878, BC144851, BY547428
      Consensus CDS
      CCDS22552.1
      UniProtKB/Swiss-Prot
      Q3V3Z3
      Related
      ENSMUSP00000074155.4, ENSMUST00000074570.10
      Conserved Domains (3) summary
      cd14964
      Location:243267
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:241513
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. NM_001145972.1NP_001139444.1  adhesion G-protein coupled receptor G5 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001139444.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK028878, BC144851, BY547428
      Consensus CDS
      CCDS52637.1
      UniProtKB/Swiss-Prot
      Q3V3Z3
      Related
      ENSMUSP00000132628.2, ENSMUST00000166802.9
      Conserved Domains (3) summary
      cd14964
      Location:244268
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:242514
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      95648439..95669921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312886.1XP_017168375.1  adhesion G-protein coupled receptor G5 isoform X2

      UniProtKB/Swiss-Prot
      Q3V3Z3
      Conserved Domains (3) summary
      cd14964
      Location:244268
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:242514
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. XM_017312885.1XP_017168374.1  adhesion G-protein coupled receptor G5 isoform X2

      UniProtKB/Swiss-Prot
      Q3V3Z3
      Conserved Domains (3) summary
      cd14964
      Location:244268
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:242514
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    3. XM_011248425.1XP_011246727.1  adhesion G-protein coupled receptor G5 isoform X3

      See identical proteins and their annotated locations for XP_011246727.1

      Conserved Domains (3) summary
      cd14964
      Location:189214
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:130174
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:188460
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    4. XM_017312884.1XP_017168373.1  adhesion G-protein coupled receptor G5 isoform X2

      UniProtKB/Swiss-Prot
      Q3V3Z3
      Conserved Domains (3) summary
      cd14964
      Location:244268
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:242514
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    5. XM_011248422.1XP_011246724.1  adhesion G-protein coupled receptor G5 isoform X1

      See identical proteins and their annotated locations for XP_011246724.1

      UniProtKB/Swiss-Prot
      Q3V3Z3
      Conserved Domains (3) summary
      cd14964
      Location:243267
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:184228
      GPS; GPCR proteolysis site, GPS, motif
      cl28897
      Location:241513
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
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