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    Gas2l2 growth arrest-specific 2 like 2 [ Mus musculus (house mouse) ]

    Gene ID: 237891, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gas2l2provided by MGI
    Official Full Name
    growth arrest-specific 2 like 2provided by MGI
    Primary source
    MGI:MGI:3652048
    See related
    Ensembl:ENSMUSG00000020686
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Biased expression in ovary adult (RPKM 1.5), lung adult (RPKM 1.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Gas2l2 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83312461..83320347, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83421635..83429521, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83235404..83242957, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene adaptor-related protein complex 2, beta 1 subunit Neighboring gene predicted gene, 23951 Neighboring gene RAS-like, family 10, member B Neighboring gene RIKEN cDNA 1700020L24 gene Neighboring gene matrix metallopeptidase 28 (epilysin) Neighboring gene TATA-box binding protein associated factor 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein alpha-subunit binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cytoskeletal anchor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables cytoskeletal anchor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with ciliary basal body IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    colocalizes_with ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with microtubule plus-end ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with stress fiber ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013759.2NP_001013781.1  GAS2-like protein 2

      See identical proteins and their annotated locations for NP_001013781.1

      Status: VALIDATED

      Source sequence(s)
      BB806501, BC147480
      Consensus CDS
      CCDS25164.1
      UniProtKB/Swiss-Prot
      Q5SSG4
      Related
      ENSMUSP00000051907.3, ENSMUST00000052521.9
      Conserved Domains (2) summary
      cd00014
      Location:34159
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam02187
      Location:207274
      GAS2; Growth-Arrest-Specific Protein 2 Domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      83312461..83320347 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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