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    Crem cAMP responsive element modulator [ Mus musculus (house mouse) ]

    Gene ID: 12916, updated on 24-Jul-2021

    Summary

    Official Symbol
    Cremprovided by MGI
    Official Full Name
    cAMP responsive element modulatorprovided by MGI
    Primary source
    MGI:MGI:88495
    See related
    Ensembl:ENSMUSG00000063889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IC; ICER; ICERI
    Summary
    This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]
    Expression
    Biased expression in testis adult (RPKM 21.9), liver adult (RPKM 1.8) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Crem in Genome Data Viewer
    Location:
    18; 18 A1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (3263181..3337688, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (3266354..3337773, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (3266352..3337587, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor, pseudogene 152 Neighboring gene vomeronasal 1 receptor, 238 Neighboring gene predicted gene 6225 Neighboring gene cullin 2 Neighboring gene profilin 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of ATF4-CREB1 transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
     
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription regulator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cAMP-responsive element modulator
    Names
    cAMP responsive element moderator
    inducible cAMP early repressor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110850.2NP_001104320.1  cAMP-responsive element modulator isoform 4

      See identical proteins and their annotated locations for NP_001104320.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4, also known as alpha gamma) lacks three alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AY738716, BP770366, BQ556287
      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000115336.2, ENSMUST00000137568.8
      Conserved Domains (2) summary
      cd14690
      Location:177231
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    2. NM_001110851.1NP_001104321.1  cAMP-responsive element modulator isoform 7

      See identical proteins and their annotated locations for NP_001104321.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) contains multiple differences in the UTRs and coding region, including a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (7) contains a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AK009841, AK010806, AK161366
      Consensus CDS
      CCDS50213.1
      UniProtKB/TrEMBL
      Q3TTH6, Q9CQ87
      Related
      ENSMUSP00000122282.2, ENSMUST00000142690.2
      Conserved Domains (1) summary
      pfam02173
      Location:96135
      pKID; pKID domain
    3. NM_001110852.1NP_001104322.1  cAMP-responsive element modulator isoform 8

      See identical proteins and their annotated locations for NP_001104322.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) contains multiple differences in the UTRs and coding region, including a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (8) contains a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AK010806
      Consensus CDS
      CCDS50212.1
      UniProtKB/TrEMBL
      Q9CQ87
      Related
      ENSMUSP00000121210.2, ENSMUST00000149803.8
      Conserved Domains (1) summary
      pfam02173
      Location:4786
      pKID; pKID domain
    4. NM_001110853.2NP_001104323.1  cAMP-responsive element modulator isoform 9

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5'UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (9) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK015641, AK076797, BP770366, BQ556287
      Consensus CDS
      CCDS50211.1
      UniProtKB/TrEMBL
      E9PV35, Q9D599
      Related
      ENSMUSP00000121118.2, ENSMUST00000122958.8
      Conserved Domains (2) summary
      cd14690
      Location:248302
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:5998
      pKID; pKID domain
    5. NM_001110854.1NP_001104324.2  cAMP-responsive element modulator isoform 10

      See identical proteins and their annotated locations for NP_001104324.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) contains multiple differences in the UTRs and coding region, including lacking multiple exons, compared to variant 1. It represents use of an alternate promoter and contains an alternate 5' coding region. The encoded isoform (10) is shorter and has distinct N- and C- termini, compared to isoform 1.
      Source sequence(s)
      AJ311667, AY738716, BE689077, BP770366, BQ556287
      Consensus CDS
      CCDS50210.2
      UniProtKB/Swiss-Prot
      P27699
      UniProtKB/TrEMBL
      F6QWT6
      Related
      ENSMUSP00000119194.3, ENSMUST00000154705.8
      Conserved Domains (1) summary
      cd14690
      Location:69123
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    6. NM_001110855.1NP_001104325.2  cAMP-responsive element modulator isoform 11

      See identical proteins and their annotated locations for NP_001104325.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) contains multiple differences in the UTRs and coding region, including lacking multiple exons, compared to variant 1. It represents use of an alternate promoter and contains an alternate 5' coding region. The encoded isoform (11) is shorter and has distinct N- and C- termini, compared to isoform 1.
      Source sequence(s)
      AJ292222, AY738716, BE689077, BP770366, BQ556287
      Consensus CDS
      CCDS50209.2
      UniProtKB/Swiss-Prot
      P27699
      UniProtKB/TrEMBL
      F6VJ22, Q78Z98
      Related
      ENSMUSP00000118578.3, ENSMUST00000151084.8
      Conserved Domains (1) summary
      cd14690
      Location:57111
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    7. NM_001110856.2NP_001104326.1  cAMP-responsive element modulator isoform 2

      See identical proteins and their annotated locations for NP_001104326.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2, also known as epsilon or tau 1 alpha) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AY738718, BP770366, BQ556287
      Consensus CDS
      CCDS50214.1
      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000119353.2, ENSMUST00000131899.8
      Conserved Domains (2) summary
      cd14690
      Location:238292
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    8. NM_001110857.2NP_001104327.1  cAMP-responsive element modulator isoform 5

      See identical proteins and their annotated locations for NP_001104327.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5, also known as beta) lacks two alternate in-frame exons, compared to variant 1. The structure of this variant is characterized in PMID: 1847666. The encoded isoform (5) is shorter than isoform 1.
      Source sequence(s)
      AC117589
      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:189243
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    9. NM_001110858.2NP_001104328.1  cAMP-responsive element modulator isoform 6

      See identical proteins and their annotated locations for NP_001104328.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6, also known as gamma) lacks three alternate in-frame exons, compared to variant 1. The structure of this variant is characterized in PMID: 1847666. The encoded isoform (6) is shorter than isoform 1.
      Source sequence(s)
      AC117589
      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:177231
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    10. NM_001110859.2NP_001104329.1  cAMP-responsive element modulator isoform 1

      See identical proteins and their annotated locations for NP_001104329.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1, also known as tau) encodes the longest isoform (1). The structure of this variant is described in PMID: 1370576.
      Source sequence(s)
      AC117589
      Consensus CDS
      CCDS50215.1
      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:301355
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    11. NM_001271503.1NP_001258432.1  cAMP-responsive element modulator isoform 12

      See identical proteins and their annotated locations for NP_001258432.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12, also known as tau 1 gamma) lacks two alternate in-frame exons, compared to variant 1. The encoded isoform (12) is shorter than isoform 1.
      Source sequence(s)
      AC117589, AY738715
      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000119638.2, ENSMUST00000146265.8
      Conserved Domains (2) summary
      cd14690
      Location:226280
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    12. NM_001271504.1NP_001258433.1  cAMP-responsive element modulator isoform 13

      See identical proteins and their annotated locations for NP_001258433.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13, also known as tau 1 alpha gamma) lacks two alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (13) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AY738717
      Consensus CDS
      CCDS70863.1
      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:226280
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    13. NM_001271505.1NP_001258434.1  cAMP-responsive element modulator isoform 14

      See identical proteins and their annotated locations for NP_001258434.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14, also known as tau 2 alpha) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (14) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AY738719
      Consensus CDS
      CCDS70862.1
      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000123515.2, ENSMUST00000152900.8
      Conserved Domains (2) summary
      cd14690
      Location:252306
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    14. NM_001271506.1NP_001258435.1  cAMP-responsive element modulator isoform 15

      See identical proteins and their annotated locations for NP_001258435.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15, also known as tau alpha gamma) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (15) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589, AY738721
      Consensus CDS
      CCDS70864.1
      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000121541.2, ENSMUST00000130455.8
      Conserved Domains (2) summary
      cd14690
      Location:289343
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    15. NM_001311066.1NP_001297995.1  cAMP-responsive element modulator isoform 16

      See identical proteins and their annotated locations for NP_001297995.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) lacks part of the 5' coding region, uses an alternate 5'-terminal exon and a downstream in-frame start codon, compared to variant 1. The encoded isoform (16) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC117589, AK076797, BP770366, BP771675, CX217456
      Consensus CDS
      CCDS79584.1
      UniProtKB/TrEMBL
      D3Z326
      Related
      ENSMUSP00000121352.2, ENSMUST00000124747.8
      Conserved Domains (1) summary
      cd14690
      Location:46100
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    16. NM_001311067.1NP_001297996.1  cAMP-responsive element modulator isoform 17

      See identical proteins and their annotated locations for NP_001297996.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) lacks part of the 5' coding region, uses an alternate 5'-terminal exon and an alternate start codon, compared to variant 1. The encoded isoform (17) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC117589
      Consensus CDS
      CCDS79585.1
      UniProtKB/TrEMBL
      D3Z6A5
      Related
      ENSMUSP00000061925.7, ENSMUST00000049942.13
      Conserved Domains (1) summary
      cd14690
      Location:63117
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    17. NM_001374833.1NP_001361762.1  cAMP-responsive element modulator isoform 18

      Status: REVIEWED

      Source sequence(s)
      AC117589
      Consensus CDS
      CCDS89179.1
      Related
      ENSMUSP00000121388.2, ENSMUST00000156234.8
      Conserved Domains (2) summary
      cd14690
      Location:285339
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    18. NM_013498.3NP_038526.2  cAMP-responsive element modulator isoform 3

      See identical proteins and their annotated locations for NP_038526.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3, also known as alpha) lacks two alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC117589
      Consensus CDS
      CCDS29031.2
      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:189243
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain

    RNA

    1. NR_073193.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) contains multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC117589, AY738720

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      3263181..3337688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525570.3XP_006525633.1  cAMP-responsive element modulator isoform X23

      UniProtKB/TrEMBL
      D3Z011
      Conserved Domains (2) summary
      cd14690
      Location:224278
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:3574
      pKID; pKID domain
    2. XM_030250301.2XP_030106161.1  cAMP-responsive element modulator isoform X9

      Conserved Domains (2) summary
      cd14690
      Location:261315
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:84123
      pKID; pKID domain
    3. XM_030250300.2XP_030106160.1  cAMP-responsive element modulator isoform X7

      Conserved Domains (2) summary
      cd14690
      Location:273327
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:84123
      pKID; pKID domain
    4. XM_030250303.2XP_030106163.1  cAMP-responsive element modulator isoform X18

      Conserved Domains (2) summary
      cd14690
      Location:236290
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:5998
      pKID; pKID domain
    5. XM_006525579.4XP_006525642.1  cAMP-responsive element modulator isoform X39

      See identical proteins and their annotated locations for XP_006525642.1

      Related
      ENSMUSP00000114280.2, ENSMUST00000147138.8
      Conserved Domains (1) summary
      cd14690
      Location:69123
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    6. XM_006525580.4XP_006525643.1  cAMP-responsive element modulator isoform X40

      See identical proteins and their annotated locations for XP_006525643.1

      Related
      ENSMUSP00000115423.2, ENSMUST00000140332.8
      Conserved Domains (1) summary
      cd14690
      Location:57111
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    7. XM_030250313.2XP_030106173.1  cAMP-responsive element modulator isoform X41

      Conserved Domains (1) summary
      cd14690
      Location:46100
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    8. XM_030250306.2XP_030106166.1  cAMP-responsive element modulator isoform X27

      Conserved Domains (2) summary
      cd14690
      Location:222276
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    9. XM_036160962.1XP_036016855.1  cAMP-responsive element modulator isoform X19

      Conserved Domains (2) summary
      cd14690
      Location:236290
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    10. XM_036160968.1XP_036016861.1  cAMP-responsive element modulator isoform X37

      Related
      ENSMUSP00000120557.2, ENSMUST00000123672.8
      Conserved Domains (2) summary
      cd14690
      Location:161215
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    11. XM_036160959.1XP_036016852.1  cAMP-responsive element modulator isoform X5

      Conserved Domains (2) summary
      cd14690
      Location:285339
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    12. XM_006525565.5XP_006525628.1  cAMP-responsive element modulator isoform X15

      See identical proteins and their annotated locations for XP_006525628.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000127353.2, ENSMUST00000165086.8
      Conserved Domains (2) summary
      cd14690
      Location:238292
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    13. XM_036160966.1XP_036016859.1  cAMP-responsive element modulator isoform X26

      Conserved Domains (2) summary
      cd14690
      Location:222276
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    14. XM_030250309.2XP_030106169.1  cAMP-responsive element modulator isoform X34

      Conserved Domains (2) summary
      cd14690
      Location:173227
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    15. XM_030250308.1XP_030106168.1  cAMP-responsive element modulator isoform X28

      Conserved Domains (2) summary
      cd14690
      Location:210264
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    16. XM_036160967.1XP_036016860.1  cAMP-responsive element modulator isoform X29

      Conserved Domains (2) summary
      cd14690
      Location:210264
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    17. XM_036160960.1XP_036016853.1  cAMP-responsive element modulator isoform X8

      Conserved Domains (2) summary
      cd14690
      Location:273327
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:96135
      pKID; pKID domain
    18. XM_006525561.5XP_006525624.1  cAMP-responsive element modulator isoform X10

      See identical proteins and their annotated locations for XP_006525624.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000080780.6, ENSMUST00000082141.12
      Conserved Domains (2) summary
      cd14690
      Location:252306
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    19. XM_030250311.1XP_030106171.1  cAMP-responsive element modulator isoform X36

      Conserved Domains (2) summary
      cd14690
      Location:161215
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    20. XM_030250305.1XP_030106165.1  cAMP-responsive element modulator isoform X24

      Conserved Domains (2) summary
      cd14690
      Location:224278
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    21. XM_036160965.1XP_036016858.1  cAMP-responsive element modulator isoform X25

      Conserved Domains (2) summary
      cd14690
      Location:224278
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    22. XM_006525566.5XP_006525629.1  cAMP-responsive element modulator isoform X17

      Conserved Domains (2) summary
      cd14690
      Location:236290
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    23. XM_036160969.1XP_036016862.1  cAMP-responsive element modulator isoform X38

      Conserved Domains (2) summary
      cd14690
      Location:149203
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:3574
      pKID; pKID domain
    24. XM_030250310.2XP_030106170.1  cAMP-responsive element modulator isoform X35

      Related
      ENSMUSP00000115471.2, ENSMUST00000130599.8
      Conserved Domains (2) summary
      cd14690
      Location:173227
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4786
      pKID; pKID domain
    25. XM_030250302.1XP_030106162.1  cAMP-responsive element modulator isoform X11

      Conserved Domains (2) summary
      cd14690
      Location:252306
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    26. XM_036160964.1XP_036016857.1  cAMP-responsive element modulator isoform X23

      Related
      ENSMUSP00000120349.2, ENSMUST00000144496.8
      Conserved Domains (2) summary
      cd14690
      Location:224278
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:3574
      pKID; pKID domain
    27. XM_036160963.1XP_036016856.1  cAMP-responsive element modulator isoform X22

      Conserved Domains (2) summary
      cd14690
      Location:224278
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:3574
      pKID; pKID domain
    28. XM_006525576.4XP_006525639.1  cAMP-responsive element modulator isoform X33

      See identical proteins and their annotated locations for XP_006525639.1

      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:177231
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    29. XM_006525575.4XP_006525638.1  cAMP-responsive element modulator isoform X32

      See identical proteins and their annotated locations for XP_006525638.1

      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:177231
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    30. XM_006525574.4XP_006525637.1  cAMP-responsive element modulator isoform X31

      See identical proteins and their annotated locations for XP_006525637.1

      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:189243
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    31. XM_006525573.4XP_006525636.1  cAMP-responsive element modulator isoform X30

      See identical proteins and their annotated locations for XP_006525636.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000122051.2, ENSMUST00000154135.8
      Conserved Domains (2) summary
      cd14690
      Location:189243
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    32. XM_006525564.4XP_006525627.1  cAMP-responsive element modulator isoform X14

      UniProtKB/TrEMBL
      D3YXV5
      Related
      ENSMUSP00000118267.2, ENSMUST00000151311.8
      Conserved Domains (2) summary
      cd14690
      Location:240294
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    33. XM_006525563.4XP_006525626.1  cAMP-responsive element modulator isoform X13

      Conserved Domains (2) summary
      cd14690
      Location:240294
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:63102
      pKID; pKID domain
    34. XM_006525567.4XP_006525630.1  cAMP-responsive element modulator isoform X20

      See identical proteins and their annotated locations for XP_006525630.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000118128.2, ENSMUST00000154470.8
      Conserved Domains (2) summary
      cd14690
      Location:226280
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    35. XM_017317808.2XP_017173297.1  cAMP-responsive element modulator isoform X16

      Conserved Domains (2) summary
      cd14690
      Location:238292
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    36. XM_006525557.4XP_006525620.1  cAMP-responsive element modulator isoform X4

      Related
      ENSMUSP00000118649.2, ENSMUST00000127601.8
      Conserved Domains (2) summary
      cd14690
      Location:289343
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    37. XM_006525556.4XP_006525619.1  cAMP-responsive element modulator isoform X3

      See identical proteins and their annotated locations for XP_006525619.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000025069.5, ENSMUST00000025069.11
      Conserved Domains (2) summary
      cd14690
      Location:289343
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    38. XM_006525554.4XP_006525617.1  cAMP-responsive element modulator isoform X1

      See identical proteins and their annotated locations for XP_006525617.1

      Conserved Domains (2) summary
      cd14690
      Location:301355
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    39. XM_011246820.4XP_011245122.1  cAMP-responsive element modulator isoform X1

      See identical proteins and their annotated locations for XP_011245122.1

      Conserved Domains (2) summary
      cd14690
      Location:301355
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    40. XM_006525559.2XP_006525622.1  cAMP-responsive element modulator isoform X6

      See identical proteins and their annotated locations for XP_006525622.1

      UniProtKB/TrEMBL
      D3Z7M6
      Conserved Domains (2) summary
      cd14690
      Location:273327
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:84123
      pKID; pKID domain
    41. XM_006525560.1XP_006525623.1  cAMP-responsive element modulator isoform X6

      See identical proteins and their annotated locations for XP_006525623.1

      UniProtKB/TrEMBL
      D3Z7M6
      Related
      ENSMUSP00000122179.2, ENSMUST00000154715.8
      Conserved Domains (2) summary
      cd14690
      Location:273327
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:84123
      pKID; pKID domain
    42. XM_006525562.5XP_006525625.1  cAMP-responsive element modulator isoform X12

      See identical proteins and their annotated locations for XP_006525625.1

      UniProtKB/TrEMBL
      E9PWV9
      Related
      ENSMUSP00000114780.2, ENSMUST00000126578.8
      Conserved Domains (2) summary
      cd14690
      Location:248302
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:5998
      pKID; pKID domain
    43. XM_030250315.2XP_030106175.1  cAMP-responsive element modulator isoform X42

      Related
      ENSMUSP00000122123.2, ENSMUST00000139537.2
      Conserved Domains (1) summary
      cd14690
      Location:3993
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    44. XM_006525555.5XP_006525618.1  cAMP-responsive element modulator isoform X2

      See identical proteins and their annotated locations for XP_006525618.1

      UniProtKB/Swiss-Prot
      P27699
      Related
      ENSMUSP00000121233.2, ENSMUST00000150235.8
      Conserved Domains (2) summary
      cd14690
      Location:301355
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
    45. XM_006525568.5XP_006525631.1  cAMP-responsive element modulator isoform X21

      See identical proteins and their annotated locations for XP_006525631.1

      UniProtKB/Swiss-Prot
      P27699
      Conserved Domains (2) summary
      cd14690
      Location:226280
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:112151
      pKID; pKID domain
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