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    Zfpm2 zinc finger protein, multitype 2 [ Mus musculus (house mouse) ]

    Gene ID: 22762, updated on 16-Oct-2021

    Summary

    Official Symbol
    Zfpm2provided by MGI
    Official Full Name
    zinc finger protein, multitype 2provided by MGI
    Primary source
    MGI:MGI:1334444
    See related
    Ensembl:ENSMUSG00000022306
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FOG2; FOG-2; B330005D23Rik
    Expression
    Broad expression in cerebellum adult (RPKM 6.0), CNS E14 (RPKM 3.9) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfpm2 in Genome Data Viewer
    Location:
    15 B3.1; 15 15.74 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (40518438..40967988)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (40655042..41104592)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (40486588..40936138)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 16294 Neighboring gene actin related protein 2/3 complex, subunit 1B pseudogene Neighboring gene mbt domain containing 1 pseudogene Neighboring gene peptidylprolyl isomerase A pseudogene 25 Neighboring gene predicted gene, 33353 Neighboring gene leucine rich repeat and sterile alpha motif containing 1 pseudogene Neighboring gene predicted gene, 46502 Neighboring gene predicted gene, 33557

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    NOT enables transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in atrioventricular valve morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within cardiac muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cardiac muscle tissue morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within embryonic organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic organ development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in heart development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within heart development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within lung development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitral valve formation TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in negative regulation of cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of female gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NOT acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in outflow tract morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in outflow tract septum morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cardiac muscle cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in right ventricular cardiac muscle tissue morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tricuspid valve formation TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within vasculogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within vasculogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vasculogenesis involved in coronary vascular morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in ventricular septum morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein ZFPM2
    Names
    Friend of GATA 2
    friend of GATA protein 2
    friend of GATA-1 2
    friend of GATA-2
    mFOG-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356998.1NP_001343927.1  zinc finger protein ZFPM2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC101996, AC102004, AC158556, AC163008
      Related
      ENSMUSP00000155094.2, ENSMUST00000230319.2
      Conserved Domains (2) summary
      sd00017
      Location:248267
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:245349
      zf-C2H2_8; C2H2-type zinc ribbon
    2. NM_011766.5NP_035896.1  zinc finger protein ZFPM2 isoform 1

      See identical proteins and their annotated locations for NP_035896.1

      Status: VALIDATED

      Source sequence(s)
      AC101996, AC102004, AC158556, AC163008
      Consensus CDS
      CCDS27447.1
      UniProtKB/Swiss-Prot
      Q8CCH7
      Related
      ENSMUSP00000051335.5, ENSMUST00000053467.6
      Conserved Domains (2) summary
      sd00017
      Location:301320
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:298388
      zf-C2H2_8; C2H2-type zinc ribbon

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      40518438..40967988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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