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    Ankrd33b ankyrin repeat domain 33B [ Mus musculus (house mouse) ]

    Gene ID: 67434, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ankrd33bprovided by MGI
    Official Full Name
    ankyrin repeat domain 33Bprovided by MGI
    Primary source
    MGI:MGI:1917904
    See related
    Ensembl:ENSMUSG00000022237
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610012A05Rik; 3021401C12Rik; 5730557B15Rik
    Expression
    Biased expression in lung adult (RPKM 10.0), cortex adult (RPKM 6.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ankrd33b in Genome Data Viewer
    Location:
    15; 15 B2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (31278328..31370446, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (31291479..31367802, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (31221234..31297514, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene death-associated protein Neighboring gene predicted gene, 41285 Neighboring gene family with sequence similarity 136, member B, pseudogene Neighboring gene predicted gene, 41286 Neighboring gene ropporin 1-like Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein 33B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164441.1NP_001157913.1  ankyrin repeat domain-containing protein 33B isoform 3

      See identical proteins and their annotated locations for NP_001157913.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AC115735, AC123917
      Consensus CDS
      CCDS49589.1
      UniProtKB/Swiss-Prot
      Q3U0L2
      Related
      ENSMUSP00000118984.2, ENSMUST00000123325.9
      Conserved Domains (4) summary
      cd00204
      Location:112239
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:121216
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:83136
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:116148
      ANK; ANK repeat [structural motif]
    2. NM_001357922.1NP_001344851.1  ankyrin repeat domain-containing protein 33B isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region and uses a downstream start codon compared to variant 1. It encodes isoform 4 which has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC115735, AC123917
      Conserved Domains (1) summary
      cd00204
      Location:149
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    3. NM_001357923.1NP_001344852.1  ankyrin repeat domain-containing protein 33B isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 5, which is shorter than isoform 1.
      Source sequence(s)
      AC115735, AC123917
      Conserved Domains (2) summary
      cd00204
      Location:24101
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4778
      ANK; ANK repeat [structural motif]
    4. NM_026153.3NP_080429.1  ankyrin repeat domain-containing protein 33B isoform 1

      See identical proteins and their annotated locations for NP_080429.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses an alternate splice pattern in the 3' coding region and 3' UTR, compared to variant 3. The resulting isoform (1) has a shorter and distinct C-terminus, compared to isoform 3.
      Source sequence(s)
      AC123917, AK012871, BC100327
      Consensus CDS
      CCDS27409.1
      UniProtKB/Swiss-Prot
      Q3U0L2
      Related
      ENSMUSP00000076209.5, ENSMUST00000076942.5
    5. NM_027496.3NP_081772.1  ankyrin repeat domain-containing protein 33B isoform 2

      See identical proteins and their annotated locations for NP_081772.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 3. The resulting isoform (2) lacks an internal segment near the N-terminus, compared to isoform 3.
      Source sequence(s)
      AC123917, AK017844, BC100327
      Consensus CDS
      CCDS27408.1
      UniProtKB/Swiss-Prot
      Q3U0L2
      Related
      ENSMUSP00000106040.3, ENSMUST00000110410.10
      Conserved Domains (3) summary
      cd00204
      Location:109230
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:112207
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:107139
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      31278328..31370446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159549.1XP_036015442.1  ankyrin repeat domain-containing protein 33B isoform X1

      Conserved Domains (3) summary
      sd00045
      Location:85114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:84136
      Ank_4; Ankyrin repeats (many copies)
      pfam12796
      Location:121209
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_006520155.5XP_006520218.1  ankyrin repeat domain-containing protein 33B isoform X2

      Conserved Domains (2) summary
      sd00045
      Location:85114
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:85160
      Ank_2; Ankyrin repeats (3 copies)

    RNA

    1. XR_004938864.1 RNA Sequence

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