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    Sdccag8 serologically defined colon cancer antigen 8 [ Mus musculus (house mouse) ]

    Gene ID: 76816, updated on 16-Oct-2021

    Summary

    Official Symbol
    Sdccag8provided by MGI
    Official Full Name
    serologically defined colon cancer antigen 8provided by MGI
    Primary source
    MGI:MGI:1924066
    See related
    Ensembl:ENSMUSG00000026504
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cccap; 2700048G21Rik; 5730470G24Rik
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 6.1), CNS E18 (RPKM 6.1) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sdccag8 in Genome Data Viewer
    Location:
    1; 1 H4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (176642226..176848004)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (176814660..177020438)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (178744943..178950563)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26104 Neighboring gene centrosomal protein 170 Neighboring gene microRNA 350 Neighboring gene high mobility group AT-hook 2, pseudogene 1 Neighboring gene predicted gene, 38158 Neighboring gene predicted gene 15423 Neighboring gene thymoma viral proto-oncogene 3 Neighboring gene predicted gene, 36904 Neighboring gene zinc finger and BTB domain containing 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centrosome cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in establishment of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in microtubule organizing center organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within microtubule organizing center organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tube formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in tube formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriolar satellite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centriole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in photoreceptor cell cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serologically defined colon cancer antigen 8 homolog
    Names
    centrosomal colon cancer autoantigen protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357390.1NP_001344319.1  serologically defined colon cancer antigen 8 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC144905, AC163009
      Conserved Domains (1) summary
      pfam15964
      Location:6719
      CCCAP; Centrosomal colon cancer autoantigen protein family
    2. NM_029756.3NP_084032.1  serologically defined colon cancer antigen 8 homolog isoform 1

      See identical proteins and their annotated locations for NP_084032.1

      Status: VALIDATED

      Source sequence(s)
      AF250729, AK132316
      Consensus CDS
      CCDS35798.1
      UniProtKB/Swiss-Prot
      Q80UF4
      Related
      ENSMUSP00000027785.9, ENSMUST00000027785.15
      Conserved Domains (1) summary
      pfam15964
      Location:6710
      CCCAP; Centrosomal colon cancer autoantigen protein family

    RNA

    1. NR_151682.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AF250729, AK136921
      Related
      ENSMUST00000133305.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      176642226..176848004
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243501.2XP_030099361.1  serologically defined colon cancer antigen 8 homolog isoform X2

      Conserved Domains (1) summary
      pfam15964
      Location:6709
      CCCAP; Centrosomal colon cancer autoantigen protein family
    2. XM_006497025.4XP_006497088.1  serologically defined colon cancer antigen 8 homolog isoform X1

      Conserved Domains (1) summary
      pfam15964
      Location:6718
      CCCAP; Centrosomal colon cancer autoantigen protein family
    3. XM_036154304.1XP_036010197.1  serologically defined colon cancer antigen 8 homolog isoform X3

      Conserved Domains (1) summary
      pfam15964
      Location:6674
      CCCAP; Centrosomal colon cancer autoantigen protein family
    4. XM_030243510.2XP_030099370.1  serologically defined colon cancer antigen 8 homolog isoform X5

      Conserved Domains (1) summary
      pfam15964
      Location:1574
      CCCAP; Centrosomal colon cancer autoantigen protein family
    5. XM_030243513.2XP_030099373.1  serologically defined colon cancer antigen 8 homolog isoform X7

      Conserved Domains (1) summary
      pfam15964
      Location:1565
      CCCAP; Centrosomal colon cancer autoantigen protein family
    6. XM_036154309.1XP_036010202.1  serologically defined colon cancer antigen 8 homolog isoform X6

      Conserved Domains (1) summary
      pfam15964
      Location:1563
      CCCAP; Centrosomal colon cancer autoantigen protein family
    7. XM_030243505.2XP_030099365.1  serologically defined colon cancer antigen 8 homolog isoform X4

      Conserved Domains (1) summary
      pfam15964
      Location:1599
      CCCAP; Centrosomal colon cancer autoantigen protein family

    RNA

    1. XR_003947262.2 RNA Sequence

      Related
      ENSMUST00000123409.8
    2. XR_003947261.2 RNA Sequence

    3. XR_004934888.1 RNA Sequence

    4. XR_004934886.1 RNA Sequence

    5. XR_003947264.2 RNA Sequence

    6. XR_004934890.1 RNA Sequence

    7. XR_003947271.1 RNA Sequence

    8. XR_003947267.2 RNA Sequence

    9. XR_003947270.2 RNA Sequence

    10. XR_003947265.2 RNA Sequence

    11. XR_004934887.1 RNA Sequence

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