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    Prrg1 proline rich Gla (G-carboxyglutamic acid) 1 [ Mus musculus (house mouse) ]

    Gene ID: 546336, updated on 23-Jun-2021

    Summary

    Official Symbol
    Prrg1provided by MGI
    Official Full Name
    proline rich Gla (G-carboxyglutamic acid) 1provided by MGI
    Primary source
    MGI:MGI:1917364
    See related
    Ensembl:ENSMUSG00000047996
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010007L08Rik
    Expression
    Broad expression in genital fat pad adult (RPKM 6.0), limb E14.5 (RPKM 2.8) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Prrg1 in Genome Data Viewer
    Location:
    X; X B
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (77493216..77627539, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (78449610..78583914, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (75694952..75829235, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene suppressor of zeste 12 homolog pseudogene Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 pseudogene Neighboring gene histone H3.3-like Neighboring gene ring finger protein 41 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    transmembrane gamma-carboxyglutamic acid protein 1
    Names
    ortholog of proline rich Gla (G-carboxyglutamic acid) 1 PRRG1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164275.2NP_001157747.1  transmembrane gamma-carboxyglutamic acid protein 1

      See identical proteins and their annotated locations for NP_001157747.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 3. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AK135895, AL672300, BX284111, CF915689, CJ052035, CX242928
      Consensus CDS
      CCDS53121.1
      UniProtKB/TrEMBL
      A2BFE8
      Related
      ENSMUSP00000136713.2, ENSMUST00000177904.8
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    2. NM_001289683.1NP_001276612.1  transmembrane gamma-carboxyglutamic acid protein 1

      See identical proteins and their annotated locations for NP_001276612.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AK135895, AL672300, BX284111, CF915689, CX242928
      Consensus CDS
      CCDS53121.1
      UniProtKB/TrEMBL
      A2BFE8
      Related
      ENSMUSP00000109659.2, ENSMUST00000114025.8
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    3. NM_027322.2NP_081598.1  transmembrane gamma-carboxyglutamic acid protein 1

      See identical proteins and their annotated locations for NP_081598.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 3. Variants 1, 2, and 3 encode the same protein.
      Source sequence(s)
      AK135895, AL672300, BX284111, CF915689, CJ052035, CX242928
      Consensus CDS
      CCDS53121.1
      UniProtKB/TrEMBL
      A2BFE8
      Related
      ENSMUSP00000109658.3, ENSMUST00000114024.9
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      77493216..77627539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162025.1XP_036017918.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    2. XM_006528143.4XP_006528206.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_006528206.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    3. XM_036162022.1XP_036017915.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X1

      Conserved Domains (1) summary
      smart00069
      Location:76139
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    4. XM_011247638.3XP_011245940.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X6

      See identical proteins and their annotated locations for XP_011245940.1

      UniProtKB/TrEMBL
      A2BFE8
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    5. XM_011247634.3XP_011245936.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011245936.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    6. XM_006528144.4XP_006528207.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_006528207.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    7. XM_011247633.4XP_011245935.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011245935.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    8. XM_011247637.3XP_011245939.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X6

      See identical proteins and their annotated locations for XP_011245939.1

      UniProtKB/TrEMBL
      A2BFE8
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    9. XM_011247632.3XP_011245934.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011245934.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    10. XM_017318551.3XP_017174040.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X6

      UniProtKB/TrEMBL
      A2BFE8
      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    11. XM_006528142.5XP_006528205.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_006528205.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    12. XM_030251387.2XP_030107247.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X6

      Conserved Domains (2) summary
      smart00069
      Location:265
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:128206
      TMEM171; Transmembrane protein family 171
    13. XM_011247635.2XP_011245937.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011245937.1

      Conserved Domains (1) summary
      smart00069
      Location:2487
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    14. XM_036162024.1XP_036017917.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X4

      Conserved Domains (1) summary
      smart00069
      Location:39102
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    15. XM_011247631.3XP_011245933.2  transmembrane gamma-carboxyglutamic acid protein 1 isoform X3

      Conserved Domains (2) summary
      smart00069
      Location:54117
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      pfam15471
      Location:180258
      TMEM171; Transmembrane protein family 171
    16. XM_036162023.1XP_036017916.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X2

      Conserved Domains (1) summary
      smart00069
      Location:41104
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    17. XM_036162026.1XP_036017919.1  transmembrane gamma-carboxyglutamic acid protein 1 isoform X7

      Conserved Domains (1) summary
      smart00069
      Location:54109
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
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