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    Sec11c SEC11 homolog C, signal peptidase complex subunit [ Mus musculus (house mouse) ]

    Gene ID: 66286, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sec11cprovided by MGI
    Official Full Name
    SEC11 homolog C, signal peptidase complex subunitprovided by MGI
    Primary source
    MGI:MGI:1913536
    See related
    Ensembl:ENSMUSG00000024516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec11; Sec11l3; 1810029G24Rik
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 32.7), cerebellum adult (RPKM 26.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sec11c in Genome Data Viewer
    Location:
    18; 18 E1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (65933649..65950731)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (65800578..65817660)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (65960232..65977311)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene O-acyltransferase like Neighboring gene predicted gene, 54022 Neighboring gene predicted gene, 52375 Neighboring gene predicted gene, 30094 Neighboring gene gastrin releasing peptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal peptide processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of signal peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    signal peptidase complex catalytic subunit SEC11C
    Names
    SEC11-like protein 3
    SPC21
    SPase 21 kDa subunit
    Sec11-like 3
    microsomal signal peptidase 21 kDa subunit
    NP_079744.1
    XP_006526213.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025468.2NP_079744.1  signal peptidase complex catalytic subunit SEC11C

      See identical proteins and their annotated locations for NP_079744.1

      Status: PROVISIONAL

      Source sequence(s)
      AK007641
      Consensus CDS
      CCDS29309.1
      UniProtKB/Swiss-Prot
      Q9D8V7
      Related
      ENSMUSP00000025394.7, ENSMUST00000025394.14
      Conserved Domains (1) summary
      cl10465
      Location:34167
      Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      65933649..65950731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526150.3XP_006526213.1  signal peptidase complex catalytic subunit SEC11C isoform X1

      See identical proteins and their annotated locations for XP_006526213.1

      Conserved Domains (1) summary
      cl10465
      Location:12129
      Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...
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