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    Ltbr lymphotoxin B receptor [ Mus musculus (house mouse) ]

    Gene ID: 17000, updated on 29-Jun-2021

    Summary

    Official Symbol
    Ltbrprovided by MGI
    Official Full Name
    lymphotoxin B receptorprovided by MGI
    Primary source
    MGI:MGI:104875
    See related
    Ensembl:ENSMUSG00000030339
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L; TN; Tnf; LTbe; Ltar; TNF-; TNFR; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III
    Expression
    Broad expression in duodenum adult (RPKM 103.9), adrenal adult (RPKM 86.6) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ltbr in Genome Data Viewer
    Location:
    6 F3; 6 59.32 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (125283534..125291026, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125306571..125313885, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (125256589..125263888, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930417O13 gene Neighboring gene tubulin, alpha 3A Neighboring gene sodium channel, nonvoltage-gated 1 alpha Neighboring gene tumor necrosis factor receptor superfamily, member 1a Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 6 Neighboring gene predicted gene, 52918

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    tumor necrosis factor receptor superfamily member 3
    Names
    LT-beta receptor
    TNF receptor-related protein
    lymphotoxin-beta receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010736.4NP_034866.1  tumor necrosis factor receptor superfamily member 3 precursor

      See identical proteins and their annotated locations for NP_034866.1

      Status: VALIDATED

      Source sequence(s)
      BC138591, CD741514, CJ066059
      Consensus CDS
      CCDS20549.1
      UniProtKB/Swiss-Prot
      P50284
      UniProtKB/TrEMBL
      B2RRV3
      Related
      ENSMUSP00000032489.8, ENSMUST00000032489.8
      Conserved Domains (3) summary
      cd00185
      Location:172212
      TNFRSF; CRD2 [structural motif]
      cd10578
      Location:11170
      TNFRSF3; Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), also known as lymphotoxin beta receptor (LTBR)
      cl22855
      Location:148212
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      125283534..125291026 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165897.1XP_036021790.1  tumor necrosis factor receptor superfamily member 3 isoform X1

      Conserved Domains (3) summary
      cd00185
      Location:172212
      TNFRSF; CRD2 [structural motif]
      cd10578
      Location:11170
      TNFRSF3; Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), also known as lymphotoxin beta receptor (LTBR)
      cl22855
      Location:148212
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
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