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    Dctpp1 dCTP pyrophosphatase 1 [ Mus musculus (house mouse) ]

    Gene ID: 66422, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dctpp1provided by MGI
    Official Full Name
    dCTP pyrophosphatase 1provided by MGI
    Primary source
    MGI:MGI:1913672
    See related
    Ensembl:ENSMUSG00000042462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RS21-; RS21-C6; AI854235; 2410015N17Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 40.4), liver E14.5 (RPKM 38.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dctpp1 in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126856131..126859839, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127256959..127260667, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134400473..134404181, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4532 Neighboring gene zinc finger protein 553 Neighboring gene zinc finger protein 771 Neighboring gene selenophosphate synthetase 2 Neighboring gene ribosomal protein, large, P1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dCTP diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables dCTP diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleoside-triphosphate diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleoside-triphosphate diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables pyrimidine deoxyribonucleotide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyrophosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA protection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in DNA protection ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dCTP catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in dCTP catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleoside triphosphate catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in nucleoside triphosphate catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    NOT located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    dCTP pyrophosphatase 1
    Names
    XTP3-transactivated gene A protein homolog
    dCTPase 1
    deoxycytidine-triphosphatase 1
    NP_075692.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023203.1NP_075692.1  dCTP pyrophosphatase 1

      See identical proteins and their annotated locations for NP_075692.1

      Status: PROVISIONAL

      Source sequence(s)
      AF110764
      Consensus CDS
      CCDS21862.1
      UniProtKB/Swiss-Prot
      Q9QY93
      Related
      ENSMUSP00000047845.5, ENSMUST00000035276.5
      Conserved Domains (1) summary
      cd11537
      Location:35125
      NTP-PPase_RS21-C6_like; Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126856131..126859839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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