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    Pvalb parvalbumin [ Mus musculus (house mouse) ]

    Gene ID: 19293, updated on 20-Jul-2021

    Summary

    Official Symbol
    Pvalbprovided by MGI
    Official Full Name
    parvalbuminprovided by MGI
    Primary source
    MGI:MGI:97821
    See related
    Ensembl:ENSMUSG00000005716
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PV; Pva; Parv
    Expression
    Biased expression in cerebellum adult (RPKM 192.6), mammary gland adult (RPKM 147.4) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Pvalb in Genome Data Viewer
    Location:
    15 E1; 15 36.93 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (78075312..78090600, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (78191112..78206400, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (78021547..78036781, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, gamma subunit 2 Neighboring gene RIKEN cDNA A730060N03 gene Neighboring gene intraflagellar transport 27 Neighboring gene neutrophil cytosolic factor 4 Neighboring gene microRNA 7676-1 Neighboring gene colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cuticular plate ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in stereocilium ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001330686.1NP_001317615.1  parvalbumin alpha

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI645659, AK131986, DV051867
      Consensus CDS
      CCDS27609.1
      UniProtKB/Swiss-Prot
      P32848
      UniProtKB/TrEMBL
      Q545M7
      Related
      ENSMUSP00000005860.10, ENSMUST00000005860.16
      Conserved Domains (1) summary
      cd16254
      Location:9109
      EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin
    2. NM_013645.4NP_038673.2  parvalbumin alpha

      See identical proteins and their annotated locations for NP_038673.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AA467036, AI645659, AL589692, CK622340, DV051867
      Consensus CDS
      CCDS27609.1
      UniProtKB/Swiss-Prot
      P32848
      UniProtKB/TrEMBL
      Q545M7
      Related
      ENSMUSP00000112598.2, ENSMUST00000120592.2
      Conserved Domains (1) summary
      cd16254
      Location:9109
      EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      78075312..78090600 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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