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    Lgi1 leucine-rich repeat LGI family, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 56839, updated on 8-Jul-2021

    Summary

    Official Symbol
    Lgi1provided by MGI
    Official Full Name
    leucine-rich repeat LGI family, member 1provided by MGI
    Primary source
    MGI:MGI:1861691
    See related
    Ensembl:ENSMUSG00000067242
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BB130740
    Expression
    Biased expression in cortex adult (RPKM 19.4), frontal lobe adult (RPKM 15.9) and 5 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lgi1 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (38253135..38297387)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (38264687..38308939)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (38339272..38383429)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene FRA10AC1 homolog (human) Neighboring gene predicted gene, 32574 Neighboring gene predicted gene, 32491 Neighboring gene predicted gene, 32771 Neighboring gene predicted gene, 52382 Neighboring gene predicted gene 9886 Neighboring gene predicted gene, 32960

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic cleft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic cleft IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    leucine-rich glioma-inactivated protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020278.3NP_064674.1  leucine-rich glioma-inactivated protein 1 precursor

      See identical proteins and their annotated locations for NP_064674.1

      Status: VALIDATED

      Source sequence(s)
      BC066090, CJ133398
      Consensus CDS
      CCDS29786.1
      UniProtKB/Swiss-Prot
      Q9JIA1
      Related
      ENSMUSP00000143128.2, ENSMUST00000198518.5
      Conserved Domains (4) summary
      TIGR00864
      Location:146221
      PCC; polycystin cation channel protein
      sd00031
      Location:7192
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:317363
      EPTP; EPTP domain
      pfam13855
      Location:91151
      LRR_8; Leucine rich repeat

    RNA

    1. NR_157558.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK031996, BC066090, CJ133398
      Related
      ENSMUST00000087252.12
    2. NR_157559.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC112153, AC116871

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      38253135..38297387
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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