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    Lamp5 lysosomal-associated membrane protein family, member 5 [ Mus musculus (house mouse) ]

    Gene ID: 76161, updated on 6-May-2021

    Summary

    Official Symbol
    Lamp5provided by MGI
    Official Full Name
    lysosomal-associated membrane protein family, member 5provided by MGI
    Primary source
    MGI:MGI:1923411
    See related
    Ensembl:ENSMUSG00000027270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BAD-; LAMP-5; BAD-LAMP; 3110035N03Rik; 6330527O06Rik
    Expression
    Biased expression in cortex adult (RPKM 56.6), frontal lobe adult (RPKM 36.0) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lamp5 in Genome Data Viewer
    Location:
    2; 2 F3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (135893945..135911837)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (136052025..136069917)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (135883663..135895653)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phospholipase C, beta 4 Neighboring gene uncharacterized LOC118568538 Neighboring gene predicted gene, 26227 Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene predicted gene 14218 Neighboring gene predicted gene, 39942

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in establishment of protein localization to organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendrite membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in early endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lysosome-associated membrane glycoprotein 5
    Names
    LAMP family protein C20orf103 homolog
    Protein C20orf103
    brain and dendritic cell-associated LAMP
    brain-associated LAMP-like protein
    lysosome-associated membrane protein 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356548.1NP_001343477.1  lysosome-associated membrane glycoprotein 5 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AL845354, AL928798
      Consensus CDS
      CCDS16789.1
      Conserved Domains (1) summary
      pfam01299
      Location:43213
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)
    2. NM_029530.3NP_083806.2  lysosome-associated membrane glycoprotein 5 precursor

      See identical proteins and their annotated locations for NP_083806.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AL845354, AL928798
      Consensus CDS
      CCDS16789.1
      UniProtKB/Swiss-Prot
      Q9D387
      Related
      ENSMUSP00000061180.7, ENSMUST00000057503.7
      Conserved Domains (1) summary
      pfam01299
      Location:43213
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      135893945..135911837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319318.2XP_017174807.1  lysosome-associated membrane glycoprotein 5 isoform X2

      UniProtKB/Swiss-Prot
      Q9D387
      Conserved Domains (1) summary
      pfam01299
      Location:2495
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)
    2. XM_036162664.1XP_036018557.1  lysosome-associated membrane glycoprotein 5 isoform X1

      Conserved Domains (1) summary
      pfam01299
      Location:43213
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)

    RNA

    1. XR_004940765.1 RNA Sequence

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