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    Mobp myelin-associated oligodendrocytic basic protein [ Mus musculus (house mouse) ]

    Gene ID: 17433, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mobpprovided by MGI
    Official Full Name
    myelin-associated oligodendrocytic basic proteinprovided by MGI
    Primary source
    MGI:MGI:108511
    See related
    Ensembl:ENSMUSG00000032517
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOBP1; MOBP69; MOBP73; MOBP81; R74645; MOBP155; MOBP170; AI835053; AI839848
    Expression
    Biased expression in cerebellum adult (RPKM 138.0), cortex adult (RPKM 97.6) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mobp in Genome Data Viewer
    Location:
    9 F4; 9 71.41 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (119978740..120010554)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (120149742..120181488)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (120058860..120085209)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, H/ACA box 62 Neighboring gene ribosomal protein SA Neighboring gene predicted gene 5922 Neighboring gene predicted gene, 38642 Neighboring gene predicted gene, 47059

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables myosin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of myelin sheath ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cortical actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in myelin sheath HDA PubMed 
    located_in myelin sheath ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    myelin-associated oligodendrocyte basic protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039365.3NP_001034454.1  myelin-associated oligodendrocyte basic protein isoform b

      See identical proteins and their annotated locations for NP_001034454.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 3' terminal exon compared to variant 1. The resulting protein (isoform b) is longer and has a distinct C-terminus compared to isoform a.
      Source sequence(s)
      AI839250, AK140055
      Consensus CDS
      CCDS23626.1
      UniProtKB/Swiss-Prot
      Q9D2P8
      Related
      ENSMUSP00000071084.8, ENSMUST00000068698.15
      Conserved Domains (2) summary
      PTZ00449
      Location:79165
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cl22851
      Location:168
      PHD_SF; PHD finger superfamily
    2. NM_008614.3NP_032640.1  myelin-associated oligodendrocyte basic protein isoform a

      See identical proteins and their annotated locations for NP_032640.1

      Status: VALIDATED

      Source sequence(s)
      AK028057, BX630280
      Consensus CDS
      CCDS40808.1
      UniProtKB/Swiss-Prot
      Q9D2P8
      Related
      ENSMUSP00000091287.2, ENSMUST00000093773.8
      Conserved Domains (1) summary
      cl22851
      Location:167
      PHD_SF; PHD finger superfamily

    RNA

    1. NR_153958.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK083103, CD776657
    2. NR_153959.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC110091
    3. NR_153960.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC110091

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      119978740..120010554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004935332.1 RNA Sequence

    2. XR_004935333.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001039364.2: Suppressed sequence

      Description
      NM_001039364.2: This RefSeq has been removed because currently there is insufficient support for the transcript.
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