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    Ndrg4 N-myc downstream regulated gene 4 [ Mus musculus (house mouse) ]

    Gene ID: 234593, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ndrg4provided by MGI
    Official Full Name
    N-myc downstream regulated gene 4provided by MGI
    Primary source
    MGI:MGI:2384590
    See related
    Ensembl:ENSMUSG00000036564
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nd; Ndr; SMA; Ndr4; R74996; SMAP-8; Ndr1-rs; D8Bwg1337e
    Expression
    Biased expression in frontal lobe adult (RPKM 385.8), cerebellum adult (RPKM 322.6) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ndrg4 in Genome Data Viewer
    Location:
    8; 8 D1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (96403602..96441584)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (95676974..95714956)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (98226963..98238856)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42037 Neighboring gene gem (nuclear organelle) associated protein 8 pseudogene Neighboring gene predicted gene, 51585 Neighboring gene SET domain containing 6 Neighboring gene CCR4-NOT transcription complex, subunit 1 Neighboring gene predicted gene, 26493

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC7067

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein NDRG4
    Names
    N-myc downstream regulated 1, related sequence
    N-myc downstream-regulated gene 4 protein
    protein Ndr4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195006.2NP_001181935.1  protein NDRG4 isoform A

      See identical proteins and their annotated locations for NP_001181935.1

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Consensus CDS
      CCDS57634.1
      UniProtKB/Swiss-Prot
      Q8BTG7
      Related
      ENSMUSP00000072883.8, ENSMUST00000073139.14
      Conserved Domains (1) summary
      pfam03096
      Location:8290
      Ndr; Ndr family
    2. NM_001372421.1NP_001359350.1  protein NDRG4 isoform C precursor

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:60342
      Ndr; Ndr family
    3. NM_001372423.1NP_001359352.1  protein NDRG4 isoform C precursor

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Consensus CDS
      CCDS90441.1
      Related
      ENSMUSP00000036226.8, ENSMUST00000041318.14
      Conserved Domains (1) summary
      pfam03096
      Location:60342
      Ndr; Ndr family
    4. NM_001372425.1NP_001359354.1  protein NDRG4 isoform D precursor

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:60342
      Ndr; Ndr family
    5. NM_001372426.1NP_001359355.1  protein NDRG4 isoform D precursor

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:60342
      Ndr; Ndr family
    6. NM_001372427.1NP_001359356.1  protein NDRG4 isoform E

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:40322
      Ndr; Ndr family
    7. NM_001372428.1NP_001359357.1  protein NDRG4 isoform E

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:40322
      Ndr; Ndr family
    8. NM_001372429.1NP_001359358.1  protein NDRG4 isoform F

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:40322
      Ndr; Ndr family
    9. NM_001372430.1NP_001359359.1  protein NDRG4 isoform G

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:40306
      Ndr; Ndr family
    10. NM_001372431.1NP_001359360.1  protein NDRG4 isoform H

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:8289
      Ndr; Ndr family
    11. NM_001372432.1NP_001359361.1  protein NDRG4 isoform I

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:8289
      Ndr; Ndr family
    12. NM_001372433.1NP_001359362.1  protein NDRG4 isoform J

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:8274
      Ndr; Ndr family
    13. NM_001372434.1NP_001359363.1  protein NDRG4 isoform K

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:8269
      Ndr; Ndr family
    14. NM_001372435.1NP_001359364.1  protein NDRG4 isoform L

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Conserved Domains (1) summary
      pfam03096
      Location:8261
      Ndr; Ndr family
    15. NM_145602.4NP_663577.1  protein NDRG4 isoform B

      See identical proteins and their annotated locations for NP_663577.1

      Status: VALIDATED

      Source sequence(s)
      AC113951
      Consensus CDS
      CCDS22565.1
      UniProtKB/Swiss-Prot
      Q8BTG7
      Related
      ENSMUSP00000079495.8, ENSMUST00000080666.8
      Conserved Domains (1) summary
      pfam03096
      Location:8290
      Ndr; Ndr family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      96403602..96441584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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