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    Lynx1 Ly6/neurotoxin 1 [ Mus musculus (house mouse) ]

    Gene ID: 23936, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lynx1provided by MGI
    Official Full Name
    Ly6/neurotoxin 1provided by MGI
    Primary source
    MGI:MGI:1345180
    See related
    Ensembl:ENSMUSG00000022594
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SLURP-2; AI838844
    Expression
    Biased expression in cerebellum adult (RPKM 74.6), heart adult (RPKM 72.6) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Lynx1 in Genome Data Viewer
    Location:
    15; 15 D3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74619705..74624828, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74747856..74752979, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (74578286..74583409, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33124 Neighboring gene secreted Ly6/Plaur domain containing 2 Neighboring gene lymphocyte antigen 6 complex, locus D Neighboring gene lymphocyte antigen 6 complex, locus G6G

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acetylcholine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetylcholine receptor inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables acetylcholine receptor inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables acetylcholine receptor regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ion channel inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in anchored component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ly-6/neurotoxin-like protein 1
    Names
    GC26
    secreted Ly-6/uPAR domain-containing protein 2
    secreted Ly-6/uPAR-related protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011838.4NP_035968.1  ly-6/neurotoxin-like protein 1 precursor

      See identical proteins and their annotated locations for NP_035968.1

      Status: PROVISIONAL

      Source sequence(s)
      AC118022
      Consensus CDS
      CCDS27530.1
      UniProtKB/Swiss-Prot
      P0DP60
      Related
      ENSMUSP00000023259.9, ENSMUST00000023259.15
      Conserved Domains (1) summary
      cd00117
      Location:2194
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      74619705..74624828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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