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    Calcb calcitonin-related polypeptide, beta [ Mus musculus (house mouse) ]

    Gene ID: 116903, updated on 23-Jun-2021

    Summary

    Official Symbol
    Calcbprovided by MGI
    Official Full Name
    calcitonin-related polypeptide, betaprovided by MGI
    Primary source
    MGI:MGI:2151254
    See related
    Ensembl:ENSMUSG00000030666
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CGR; Cal; CGRP2; Calc2
    Expression
    Biased expression in thymus adult (RPKM 2.1), large intestine adult (RPKM 0.5) and 13 other tissues See more
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    Genomic context

    See Calcb in Genome Data Viewer
    Location:
    7; 7 F1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (114315790..114322603)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (114716555..114723368)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (121862157..121866879)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 21 pseudogene Neighboring gene ribosomal protein L5 pseudogene Neighboring gene INSC spindle orientation adaptor protein Neighboring gene predicted gene, 24982 Neighboring gene ribosomal protein S4-like, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Clone Names

    • MGC130530

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcitonin receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of cytosolic calcium ion concentration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    calcitonin gene-related peptide 2
    Names
    CGRP-II
    beta-type CGRP
    calcitonin gene-related peptide II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_054084.2NP_473425.2  calcitonin gene-related peptide 2 precursor

      See identical proteins and their annotated locations for NP_473425.2

      Status: VALIDATED

      Source sequence(s)
      AI324836, BC111865
      Consensus CDS
      CCDS21764.1
      UniProtKB/TrEMBL
      Q3UW96
      Related
      ENSMUSP00000032902.5, ENSMUST00000032902.11
      Conserved Domains (1) summary
      pfam00214
      Location:1125
      Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      114315790..114322603
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507212.4XP_006507275.1  calcitonin gene-related peptide 2 isoform X1

      See identical proteins and their annotated locations for XP_006507275.1

      UniProtKB/TrEMBL
      Q3UW96
      Conserved Domains (1) summary
      pfam00214
      Location:1125
      Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family
    2. XM_006507213.4XP_006507276.1  calcitonin gene-related peptide 2 isoform X1

      See identical proteins and their annotated locations for XP_006507276.1

      UniProtKB/TrEMBL
      Q3UW96
      Conserved Domains (1) summary
      pfam00214
      Location:1125
      Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family
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