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    Hdac11 histone deacetylase 11 [ Mus musculus (house mouse) ]

    Gene ID: 232232, updated on 8-Jul-2021

    Summary

    Official Symbol
    Hdac11provided by MGI
    Official Full Name
    histone deacetylase 11provided by MGI
    Primary source
    MGI:MGI:2385252
    See related
    Ensembl:ENSMUSG00000034245
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in testis adult (RPKM 59.4), cerebellum adult (RPKM 42.4) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Hdac11 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (91133652..91151674)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (91156670..91174692)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (91106809..91124677)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene nucleoporin 210 Neighboring gene predicted gene, 30364 Neighboring gene VISTA enhancer mm1314 Neighboring gene uncharacterized LOC118567405 Neighboring gene fibulin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC27683

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone deacetylase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone deacetylase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in histone deacetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oligodendrocyte development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    part_of histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone deacetylase complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone deacetylase 11
    Names
    HD11
    NP_659168.1
    XP_036021947.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144919.2NP_659168.1  histone deacetylase 11

      See identical proteins and their annotated locations for NP_659168.1

      Status: PROVISIONAL

      Source sequence(s)
      AC110256, AC131764
      Consensus CDS
      CCDS20366.1
      UniProtKB/Swiss-Prot
      Q91WA3
      UniProtKB/TrEMBL
      Q543U1
      Related
      ENSMUSP00000043828.5, ENSMUST00000041736.11
      Conserved Domains (1) summary
      cd09993
      Location:35319
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      91133652..91151674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036166054.1XP_036021947.1  histone deacetylase 11 isoform X1

      Conserved Domains (1) summary
      cd09993
      Location:16197
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

    RNA

    1. XR_003956189.1 RNA Sequence

    2. XR_003956190.1 RNA Sequence

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