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    H2ac7 H2A clustered histone 7 [ Mus musculus (house mouse) ]

    Gene ID: 319165, updated on 6-May-2021

    Summary

    Official Symbol
    H2ac7provided by MGI
    Official Full Name
    H2A clustered histone 7provided by MGI
    Primary source
    MGI:MGI:2448289
    See related
    Ensembl:ENSMUSG00000071478
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hist1h; Hist1h2ad
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H2ac7 in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23758555..23759089)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23574381..23574915)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (23666340..23666732)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene H2B clustered histone 8 Neighboring gene H2B clustered histone 7 Neighboring gene H3 clustered histone 4 Neighboring gene H4 clustered histone 4

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin silencing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H2A type 1-D
    Names
    histone 1, H2ad
    histone H2A type 1
    histone cluster 1, H2ad

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178188.4NP_835495.1  histone H2A type 1-D

      See identical proteins and their annotated locations for NP_835495.1

      Status: REVIEWED

      Source sequence(s)
      AL592149
      Consensus CDS
      CCDS26351.1
      UniProtKB/Swiss-Prot
      C0HKE1, C0HKE2, C0HKE3, C0HKE4, C0HKE5, C0HKE6, C0HKE7, C0HKE8, C0HKE9
      UniProtKB/TrEMBL
      B2RVF0
      Related
      ENSMUSP00000088281.5, ENSMUST00000090776.7
      Conserved Domains (1) summary
      PTZ00017
      Location:1130
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      23758555..23759089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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