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    Nat8 N-acetyltransferase 8 (GCN5-related) [ Mus musculus (house mouse) ]

    Gene ID: 68396, updated on 6-May-2021

    Summary

    Official Symbol
    Nat8provided by MGI
    Official Full Name
    N-acetyltransferase 8 (GCN5-related)provided by MGI
    Primary source
    MGI:MGI:1915646
    See related
    Ensembl:ENSMUSG00000030004
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cml; Cml4; CCNAT; ATase2; 0610037O16Rik
    Expression
    Biased expression in kidney adult (RPKM 43.2), duodenum adult (RPKM 18.8) and 4 other tissues See more
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    Genomic context

    See Nat8 in Genome Data Viewer
    Location:
    6; 6 C3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (85807369..85813839, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (85830387..85836857, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (85780381..85781884, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 6 Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 5 Neighboring gene prostaglandin E synthase 3, pseudogene Neighboring gene predicted gene, 38847

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables N-acetyltransferase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables cysteine-S-conjugate N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in endoplasmic reticulum ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    NOT located_in late recombination nodule ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-acetyltransferase 8
    Names
    N-acetyltransferase 8 (GCN5-related, putative)
    acetyltransferase 2
    camello-like 4
    camello-like protein 4
    cysteinyl-conjugate N-acetyltransferase
    probable N-acetyltransferase CML4
    NP_001348989.1
    NP_075944.1
    XP_006506599.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362060.1NP_001348989.1  N-acetyltransferase 8

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC161888
      Consensus CDS
      CCDS20301.1
      Conserved Domains (1) summary
      pfam00583
      Location:91193
      Acetyltransf_1; Acetyltransferase (GNAT) family
    2. NM_023455.4NP_075944.1  N-acetyltransferase 8

      See identical proteins and their annotated locations for NP_075944.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant (1). Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC161888
      Consensus CDS
      CCDS20301.1
      UniProtKB/Swiss-Prot
      Q9JIY7
      Related
      ENSMUSP00000032073.7, ENSMUST00000032073.7
      Conserved Domains (1) summary
      pfam00583
      Location:91193
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      85807369..85813839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506536.3XP_006506599.1  N-acetyltransferase 8 isoform X1

      See identical proteins and their annotated locations for XP_006506599.1

      UniProtKB/Swiss-Prot
      Q9JIY7
      Conserved Domains (1) summary
      pfam00583
      Location:91193
      Acetyltransf_1; Acetyltransferase (GNAT) family
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