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    Cox8a cytochrome c oxidase subunit 8A [ Mus musculus (house mouse) ]

    Gene ID: 12868, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cox8aprovided by MGI
    Official Full Name
    cytochrome c oxidase subunit 8Aprovided by MGI
    Primary source
    MGI:MGI:105959
    See related
    Ensembl:ENSMUSG00000035885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    COX; COX8L
    Expression
    Ubiquitous expression in duodenum adult (RPKM 1660.4), colon adult (RPKM 1505.4) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cox8a in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (7192523..7194981, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (7215158..7217616, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7289648..7292106, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene mono-ADP ribosylhydrolase 1 Neighboring gene fibronectin leucine rich transmembrane protein 1 Neighboring gene predicted gene, 38621 Neighboring gene OTU domain, ubiquitin aldehyde binding 1 Neighboring gene N(alpha)-acetyltransferase 40, NatD catalytic subunit Neighboring gene predicted gene, 22113

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cytochrome-c oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of respiratory chain complex IV IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cytochrome c oxidase subunit 8A, mitochondrial
    Names
    COX VIII-L
    cytochrome c oxidase polypeptide VIII-liver
    cytochrome c oxidase subunit 8-2
    cytochrome c oxidase subunit VIIIa
    NP_031776.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007750.2NP_031776.1  cytochrome c oxidase subunit 8A, mitochondrial precursor

      See identical proteins and their annotated locations for NP_031776.1

      Status: VALIDATED

      Source sequence(s)
      AAHY01141457, AK002218
      Consensus CDS
      CCDS29521.1
      UniProtKB/Swiss-Prot
      Q64445
      Related
      ENSMUSP00000040717.5, ENSMUST00000039758.6
      Conserved Domains (1) summary
      pfam02285
      Location:2767
      COX8; Cytochrome oxidase c subunit VIII

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      7192523..7194981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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