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    Tspan6 tetraspanin 6 [ Mus musculus (house mouse) ]

    Gene ID: 56496, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tspan6provided by MGI
    Official Full Name
    tetraspanin 6provided by MGI
    Primary source
    MGI:MGI:1926264
    See related
    Ensembl:ENSMUSG00000067377
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T245; Tm4sf; Tm4sf6; TSPAN-6; AI316786; 6720473L21Rik
    Expression
    Broad expression in CNS E18 (RPKM 40.5), whole brain E14.5 (RPKM 35.2) and 18 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tspan6 in Genome Data Viewer
    Location:
    X; X E3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (132791817..132801957, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (133891068..133901208, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (130425609..130432968, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene protocadherin 19 Neighboring gene predicted gene, 26851 Neighboring gene tenomodulin Neighboring gene sushi-repeat-containing protein, X-linked 2 Neighboring gene synaptotagmin-like 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC117923

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tetraspanin-6
    Names
    tetraspan TM4SF
    transmembrane 4 superfamily member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019656.3NP_062630.2  tetraspanin-6

      See identical proteins and their annotated locations for NP_062630.2

      Status: VALIDATED

      Source sequence(s)
      AA458002, AK167384, AV351536
      Consensus CDS
      CCDS30387.1
      UniProtKB/TrEMBL
      Q99L96
      Related
      ENSMUSP00000084838.6, ENSMUST00000087557.12
      Conserved Domains (1) summary
      pfam00335
      Location:17233
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      132791817..132801957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251428.1XP_030107288.1  tetraspanin-6 isoform X1

      Conserved Domains (1) summary
      pfam00335
      Location:17233
      Tetraspannin; Tetraspanin family
    2. XM_036162050.1XP_036017943.1  tetraspanin-6 isoform X2

      Conserved Domains (1) summary
      cd03161
      Location:24121
      TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
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