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    Tlcd4 TLC domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 99887, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tlcd4provided by MGI
    Official Full Name
    TLC domain containing 4provided by MGI
    Primary source
    MGI:MGI:1923195
    See related
    Ensembl:ENSMUSG00000028132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem56; AU018104; AW109744; 4930577M16Rik; C730036B01Rik
    Expression
    Broad expression in testis adult (RPKM 12.1), liver adult (RPKM 10.0) and 18 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tlcd4 in Genome Data Viewer
    Location:
    3; 3 G1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (120995657..121076756, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (121202008..121283108, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (120904926..120966234, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RWD domain containing 3 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 52661 Neighboring gene within bgcn homolog pseudogene Neighboring gene asparagine-linked glycosylation 14 Neighboring gene predicted gene, 33310 Neighboring gene predicted gene, 33363 Neighboring gene peptidylprolyl isomerase A pseudogene 3_1234.1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in lipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    TLC domain-containing protein 4
    Names
    transmembrane protein 56

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355678.2NP_001342607.2  TLC domain-containing protein 4

      Status: VALIDATED

      Source sequence(s)
      AC110195
      Related
      ENSMUSP00000119468.2, ENSMUST00000128909.8
      Conserved Domains (1) summary
      smart00724
      Location:45246
      TLC; TRAM, LAG1 and CLN8 homology domains
    2. NM_178936.4NP_849267.2  TLC domain-containing protein 4

      Status: VALIDATED

      Source sequence(s)
      AC110195
      Related
      ENSMUSP00000029777.8, ENSMUST00000029777.14
      Conserved Domains (1) summary
      smart00724
      Location:45246
      TLC; TRAM, LAG1 and CLN8 homology domains

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      120995657..121076756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502478.3XP_006502541.1  TLC domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006502541.1

      UniProtKB/Swiss-Prot
      Q8CGF5
      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    2. XM_011240340.2XP_011238642.1  TLC domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_011238642.1

      UniProtKB/Swiss-Prot
      Q8CGF5
      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    3. XM_011240337.2XP_011238639.1  TLC domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_011238639.1

      UniProtKB/Swiss-Prot
      Q8CGF5
      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    4. XM_030252956.2XP_030108816.1  TLC domain-containing protein 4 isoform X1

      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    5. XM_006502480.5XP_006502543.1  TLC domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006502543.1

      UniProtKB/Swiss-Prot
      Q8CGF5
      Related
      ENSMUSP00000120821.2, ENSMUST00000155309.8
      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    6. XM_011240339.2XP_011238641.1  TLC domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_011238641.1

      UniProtKB/Swiss-Prot
      Q8CGF5
      Conserved Domains (1) summary
      smart00724
      Location:58259
      TLC; TRAM, LAG1 and CLN8 homology domains
    7. XM_017319841.3XP_017175330.1  TLC domain-containing protein 4 isoform X2

      Related
      ENSMUSP00000122001.2, ENSMUST00000137234.2
      Conserved Domains (1) summary
      cl02759
      Location:58171
      TRAM_LAG1_CLN8; TLC domain
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