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    Tango2 transport and golgi organization 2 [ Mus musculus (house mouse) ]

    Gene ID: 27883, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tango2provided by MGI
    Official Full Name
    transport and golgi organization 2provided by MGI
    Primary source
    MGI:MGI:101825
    See related
    Ensembl:ENSMUSG00000013539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T10; D16H22S680; D16H22S680E
    Expression
    Ubiquitous expression in heart adult (RPKM 19.8), kidney adult (RPKM 10.4) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tango2 in Genome Data Viewer
    Location:
    16 A3; 16 11.34 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (18118689..18165962, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (18300825..18348098, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (18300918..18344025, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene DGCR8, microprocessor complex subunit Neighboring gene microRNA 1306 Neighboring gene microRNA 3618 Neighboring gene microRNA 185 Neighboring gene armadillo repeat gene deleted in velocardiofacial syndrome Neighboring gene predicted gene 15764 Neighboring gene catechol-O-methyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    transport and Golgi organization 2 homolog
    Names
    ser/Thr-rich protein T10 in DGCR region
    transport and golgi organization 2 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359108.1NP_001346037.1  transport and Golgi organization 2 homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform.
      Source sequence(s)
      AC084822
      Consensus CDS
      CCDS28019.1
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2
    2. NM_001359109.1NP_001346038.1  transport and Golgi organization 2 homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform.
      Source sequence(s)
      AC084822
      Consensus CDS
      CCDS28019.1
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2
    3. NM_001359110.1NP_001346039.1  transport and Golgi organization 2 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC084822
      Conserved Domains (1) summary
      pfam05742
      Location:2208
      TANGO2; Transport and Golgi organisation 2
    4. NM_001359111.1NP_001346040.1  transport and Golgi organization 2 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC084822
      Conserved Domains (1) summary
      pfam05742
      Location:2208
      TANGO2; Transport and Golgi organisation 2
    5. NM_138583.2NP_613049.2  transport and Golgi organization 2 homolog isoform 1

      See identical proteins and their annotated locations for NP_613049.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 2, and 3 encode the same isoform.
      Source sequence(s)
      AI837283, AK168595, BY274949
      Consensus CDS
      CCDS28019.1
      UniProtKB/TrEMBL
      Q8BTN3
      Related
      ENSMUSP00000111291.3, ENSMUST00000115628.10
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      18118689..18165962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522230.2XP_006522293.1  transport and Golgi organization 2 homolog isoform X2

      See identical proteins and their annotated locations for XP_006522293.1

      Conserved Domains (1) summary
      pfam05742
      Location:2208
      TANGO2; Transport and Golgi organisation 2
    2. XM_036159979.1XP_036015872.1  transport and Golgi organization 2 homolog isoform X1

      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2
    3. XM_017317031.3XP_017172520.1  transport and Golgi organization 2 homolog isoform X1

      UniProtKB/TrEMBL
      Q8BTN3
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2
    4. XM_036159978.1XP_036015871.1  transport and Golgi organization 2 homolog isoform X1

      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2
    5. XM_011245929.1XP_011244231.1  transport and Golgi organization 2 homolog isoform X1

      See identical proteins and their annotated locations for XP_011244231.1

      UniProtKB/TrEMBL
      Q8BTN3
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organisation 2

    RNA

    1. XR_384570.2 RNA Sequence

    2. XR_003951794.2 RNA Sequence

      Related
      ENSMUST00000128580.8
    3. XR_384571.2 RNA Sequence

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