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    Megf11 multiple EGF-like-domains 11 [ Mus musculus (house mouse) ]

    Gene ID: 214058, updated on 23-Jun-2021

    Summary

    Official Symbol
    Megf11provided by MGI
    Official Full Name
    multiple EGF-like-domains 11provided by MGI
    Primary source
    MGI:MGI:1920951
    See related
    Ensembl:ENSMUSG00000036466
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D130061K05; 2410080H04Rik
    Expression
    Biased expression in cerebellum adult (RPKM 16.3), whole brain E14.5 (RPKM 3.8) and 5 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Megf11 in Genome Data Viewer
    Location:
    9; 9 C
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (64291556..64618584)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (64385617..64714179)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (64233433..64557012)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene timeless interacting protein Neighboring gene predicted gene, 24289 Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene predicted gene, 36311 Neighboring gene RAB11A, member RAS oncogene family Neighboring gene nuclear encoded tRNA glutamine 9 (anticodon CTG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in homotypic cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in retina layer formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    multiple epidermal growth factor-like domains protein 11
    Names
    multiple EGF-like domains protein 11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134399.1NP_001127871.1  multiple epidermal growth factor-like domains protein 11 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC147560, AK051642, AK160406, BB650216, BB689543, BY275058
      Consensus CDS
      CCDS52833.1
      UniProtKB/Swiss-Prot
      Q80T91
      UniProtKB/TrEMBL
      E9Q918
      Related
      ENSMUSP00000128672.2, ENSMUST00000164113.8
      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    2. NM_172522.4NP_766110.3  multiple epidermal growth factor-like domains protein 11 isoform 2 precursor

      See identical proteins and their annotated locations for NP_766110.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' coding region, 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a distinct C terminus and is shorter than isoform 1.
      Source sequence(s)
      AK051642, BI134980, BY275058
      Consensus CDS
      CCDS23281.1
      UniProtKB/Swiss-Prot
      Q80T91
      Related
      ENSMUSP00000091349.3, ENSMUST00000093829.9
      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:243288
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      64291556..64618584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154802.1XP_036010695.1  multiple epidermal growth factor-like domains protein 11 isoform X15

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    2. XM_030244210.2XP_030100070.1  multiple epidermal growth factor-like domains protein 11 isoform X18

      Conserved Domains (1) summary
      pfam07546
      Location:2592
      EMI; EMI domain
    3. XM_006510989.3XP_006511052.1  multiple epidermal growth factor-like domains protein 11 isoform X4

      UniProtKB/Swiss-Prot
      Q80T91
      Related
      ENSMUSP00000114035.2, ENSMUST00000118485.8
      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    4. XM_006510991.5XP_006511054.1  multiple epidermal growth factor-like domains protein 11 isoform X1

      See identical proteins and their annotated locations for XP_006511054.1

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    5. XM_036154786.1XP_036010679.1  multiple epidermal growth factor-like domains protein 11 isoform X2

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    6. XM_036154800.1XP_036010693.1  multiple epidermal growth factor-like domains protein 11 isoform X14

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    7. XM_036154790.1XP_036010683.1  multiple epidermal growth factor-like domains protein 11 isoform X7

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    8. XM_036154812.1XP_036010705.1  multiple epidermal growth factor-like domains protein 11 isoform X24

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    9. XM_036154804.1XP_036010697.1  multiple epidermal growth factor-like domains protein 11 isoform X17

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    10. XM_036154795.1XP_036010688.1  multiple epidermal growth factor-like domains protein 11 isoform X10

      Related
      ENSMUSP00000065353.5, ENSMUST00000068967.11
      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    11. XM_030244209.2XP_030100069.1  multiple epidermal growth factor-like domains protein 11 isoform X13

      Conserved Domains (1) summary
      pfam07546
      Location:2592
      EMI; EMI domain
    12. XM_036154791.1XP_036010684.1  multiple epidermal growth factor-like domains protein 11 isoform X8

      Conserved Domains (4) summary
      pfam00053
      Location:274319
      Laminin_EGF; Laminin EGF domain
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:188233
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    13. XM_030244211.2XP_030100071.1  multiple epidermal growth factor-like domains protein 11 isoform X19

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    14. XM_036154794.1XP_036010687.1  multiple epidermal growth factor-like domains protein 11 isoform X9

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    15. XM_036154814.1XP_036010707.1  multiple epidermal growth factor-like domains protein 11 isoform X26

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    16. XM_036154807.1XP_036010700.1  multiple epidermal growth factor-like domains protein 11 isoform X20

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    17. XM_036154789.1XP_036010682.1  multiple epidermal growth factor-like domains protein 11 isoform X6

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    18. XM_036154788.1XP_036010681.1  multiple epidermal growth factor-like domains protein 11 isoform X5

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    19. XM_036154797.1XP_036010690.1  multiple epidermal growth factor-like domains protein 11 isoform X12

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    20. XM_036154809.1XP_036010702.1  multiple epidermal growth factor-like domains protein 11 isoform X21

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    21. XM_036154813.1XP_036010706.1  multiple epidermal growth factor-like domains protein 11 isoform X25

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    22. XM_036154803.1XP_036010696.1  multiple epidermal growth factor-like domains protein 11 isoform X16

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    23. XM_036154810.1XP_036010703.1  multiple epidermal growth factor-like domains protein 11 isoform X22

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    24. XM_036154811.1XP_036010704.1  multiple epidermal growth factor-like domains protein 11 isoform X23

      Conserved Domains (1) summary
      pfam07546
      Location:2592
      EMI; EMI domain
    25. XM_036154785.1XP_036010678.1  multiple epidermal growth factor-like domains protein 11 isoform X1

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    26. XM_036154787.1XP_036010680.1  multiple epidermal growth factor-like domains protein 11 isoform X4

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    27. XM_036154793.1XP_036010686.1  multiple epidermal growth factor-like domains protein 11 isoform X8

      Conserved Domains (4) summary
      pfam00053
      Location:274319
      Laminin_EGF; Laminin EGF domain
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:188233
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    28. XM_036154798.1XP_036010691.1  multiple epidermal growth factor-like domains protein 11 isoform X13

      Conserved Domains (1) summary
      pfam07546
      Location:2592
      EMI; EMI domain
    29. XM_036154806.1XP_036010699.1  multiple epidermal growth factor-like domains protein 11 isoform X19

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    30. XM_036154815.1XP_036010708.1  multiple epidermal growth factor-like domains protein 11 isoform X26

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    31. XM_036154796.1XP_036010689.1  multiple epidermal growth factor-like domains protein 11 isoform X11

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    32. XM_036154792.1XP_036010685.1  multiple epidermal growth factor-like domains protein 11 isoform X8

      Conserved Domains (4) summary
      pfam00053
      Location:274319
      Laminin_EGF; Laminin EGF domain
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:188233
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    33. XM_036154808.1XP_036010701.1  multiple epidermal growth factor-like domains protein 11 isoform X20

      Conserved Domains (3) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      NF033759
      Location:348682
      exchanger_TraA; outer membrane exchange protein TraA
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    34. XM_006510986.4XP_006511049.1  multiple epidermal growth factor-like domains protein 11 isoform X1

      See identical proteins and their annotated locations for XP_006511049.1

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    35. XM_036154799.1XP_036010692.1  multiple epidermal growth factor-like domains protein 11 isoform X13

      Conserved Domains (1) summary
      pfam07546
      Location:2592
      EMI; EMI domain
    36. XM_036154805.1XP_036010698.1  multiple epidermal growth factor-like domains protein 11 isoform X19

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    37. XM_036154801.1XP_036010694.1  multiple epidermal growth factor-like domains protein 11 isoform X15

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    38. XM_030244207.2XP_030100067.1  multiple epidermal growth factor-like domains protein 11 isoform X3

      Conserved Domains (2) summary
      pfam07546
      Location:2592
      EMI; EMI domain
      cl21504
      Location:274319
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    39. XM_036154816.1XP_036010709.1  multiple epidermal growth factor-like domains protein 11 isoform X27

      Conserved Domains (1) summary
      cl21504
      Location:200245
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

    RNA

    1. XR_004935367.1 RNA Sequence

    2. XR_004935365.1 RNA Sequence

    3. XR_004935370.1 RNA Sequence

    4. XR_004935371.1 RNA Sequence

    5. XR_004935373.1 RNA Sequence

    6. XR_004935374.1 RNA Sequence

    7. XR_004935368.1 RNA Sequence

    8. XR_004935366.1 RNA Sequence

    9. XR_004935369.1 RNA Sequence

    10. XR_004935372.1 RNA Sequence

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