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    Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N [ Mus musculus (house mouse) ]

    Gene ID: 20716, updated on 23-Jun-2021

    Summary

    Official Symbol
    Serpina3nprovided by MGI
    Official Full Name
    serine (or cysteine) peptidase inhibitor, clade A, member 3Nprovided by MGI
    Primary source
    MGI:MGI:105045
    See related
    Ensembl:ENSMUSG00000021091
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spi; ant; Spi2-2; Spi2.2; Spi2/e; Spi2/eb.4
    Expression
    Biased expression in subcutaneous fat pad adult (RPKM 296.6), liver adult (RPKM 171.8) and 7 other tissues See more
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    Genomic context

    See Serpina3n in Genome Data Viewer
    Location:
    12; 12 E
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (104372887..104380593)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (104406646..104414334)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (105644918..105652539)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene serine (or cysteine) peptidase inhibitor, clade A, member 3M Neighboring gene predicted gene, 40561 Neighboring gene predicted gene, 24334 Neighboring gene predicted gene, 40562

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space HDA PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    serine protease inhibitor A3N
    Names
    alpha-1 antiproteinase
    antitrypsin
    serine (or cysteine) proteinase inhibitor, clade A, member 3N
    serine protease inhibitor 2-2
    serpin A3N

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009252.2NP_033278.2  serine protease inhibitor A3N precursor

      See identical proteins and their annotated locations for NP_033278.2

      Status: VALIDATED

      Source sequence(s)
      AC117194
      Consensus CDS
      CCDS26152.1
      UniProtKB/TrEMBL
      G3X8T9
      Related
      ENSMUSP00000021506.6, ENSMUST00000021506.6
      Conserved Domains (1) summary
      cd19551
      Location:37418
      serpinA3_A1AC; serpin family A member 3, alpha 1-antichymotrypsin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      104372887..104380593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157281.1XP_036013174.1  serine protease inhibitor A3N isoform X1

      Conserved Domains (1) summary
      cd19551
      Location:37418
      serpinA3_A1AC; serpin family A member 3, alpha 1-antichymotrypsin
    2. XM_011244046.4XP_011242348.1  serine protease inhibitor A3N isoform X1

      See identical proteins and their annotated locations for XP_011242348.1

      UniProtKB/TrEMBL
      G3X8T9
      Conserved Domains (1) summary
      cd19551
      Location:37418
      serpinA3_A1AC; serpin family A member 3, alpha 1-antichymotrypsin
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