Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slco2b1 solute carrier organic anion transporter family, member 2b1 [ Mus musculus (house mouse) ]

    Gene ID: 101488, updated on 24-Jul-2021

    Summary

    Official Symbol
    Slco2b1provided by MGI
    Official Full Name
    solute carrier organic anion transporter family, member 2b1provided by MGI
    Primary source
    MGI:MGI:1351872
    See related
    Ensembl:ENSMUSG00000030737
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OAT; Slc2; OATP-B; Slc21a9; AI060904; AI852653
    Expression
    Broad expression in liver adult (RPKM 40.1), mammary gland adult (RPKM 19.5) and 17 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slco2b1 in Genome Data Viewer
    Location:
    7; 7 E1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99307011..99360547, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99657804..99711340, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (106806314..106859850, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53384 Neighboring gene predicted gene, 25409 Neighboring gene predicted gene, 34280 Neighboring gene olfactory receptor 520 Neighboring gene UTP18, small subunit (SSU) processome component, homolog pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Clone Names

    • MGC106224

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in bile acid and bile salt transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in bile acid and bile salt transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium-independent icosanoid transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier organic anion transporter family member 2B1
    Names
    solute carrier family 21 (organic anion transporter), member 9
    solute carrier family 21 member 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252530.1NP_001239459.1  solute carrier organic anion transporter family member 2B1 isoform 1

      See identical proteins and their annotated locations for NP_001239459.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
      Source sequence(s)
      AK048120, AK132394, AK163542
      Consensus CDS
      CCDS57567.1
      UniProtKB/Swiss-Prot
      Q8BXB6
      UniProtKB/TrEMBL
      Q3TQJ3, Q3V1K7
      Related
      ENSMUSP00000102703.2, ENSMUST00000107088.8
      Conserved Domains (3) summary
      cd06174
      Location:58301
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:484541
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      pfam03137
      Location:52646
      OATP; Organic Anion Transporter Polypeptide (OATP) family
    2. NM_001252531.1NP_001239460.1  solute carrier organic anion transporter family member 2B1 isoform 2

      See identical proteins and their annotated locations for NP_001239460.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains a different exon for its 5' end, which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 1. Variants 2 and 3 encode the same protein.
      Source sequence(s)
      AK041144, AK048120, BY340952
      Consensus CDS
      CCDS21485.1
      UniProtKB/Swiss-Prot
      Q8BXB6
      Related
      ENSMUSP00000102701.3, ENSMUST00000107086.9
      Conserved Domains (1) summary
      cl28910
      Location:40577
      MFS; Major Facilitator Superfamily
    3. NM_175316.3NP_780525.1  solute carrier organic anion transporter family member 2B1 isoform 2

      See identical proteins and their annotated locations for NP_780525.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains a different exon for its 5' end, which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 1. Variants 2 and 3 encode the same protein.
      Source sequence(s)
      AK048120
      Consensus CDS
      CCDS21485.1
      UniProtKB/Swiss-Prot
      Q8BXB6
      Related
      ENSMUSP00000032985.5, ENSMUST00000032985.11
      Conserved Domains (1) summary
      cl28910
      Location:40577
      MFS; Major Facilitator Superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      99307011..99360547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241641.4XP_011239943.1  solute carrier organic anion transporter family member 2B1 isoform X2

      See identical proteins and their annotated locations for XP_011239943.1

      UniProtKB/Swiss-Prot
      Q8BXB6
      Conserved Domains (1) summary
      cl28910
      Location:40577
      MFS; Major Facilitator Superfamily
    2. XM_011241640.4XP_011239942.1  solute carrier organic anion transporter family member 2B1 isoform X2

      See identical proteins and their annotated locations for XP_011239942.1

      UniProtKB/Swiss-Prot
      Q8BXB6
      Conserved Domains (1) summary
      cl28910
      Location:40577
      MFS; Major Facilitator Superfamily
    3. XM_011241638.4XP_011239940.1  solute carrier organic anion transporter family member 2B1 isoform X1

      See identical proteins and their annotated locations for XP_011239940.1

      Conserved Domains (1) summary
      cl28910
      Location:54591
      MFS; Major Facilitator Superfamily
    4. XM_011241639.1XP_011239941.1  solute carrier organic anion transporter family member 2B1 isoform X1

      See identical proteins and their annotated locations for XP_011239941.1

      Conserved Domains (1) summary
      cl28910
      Location:54591
      MFS; Major Facilitator Superfamily
    5. XM_011241637.4XP_011239939.1  solute carrier organic anion transporter family member 2B1 isoform X1

      See identical proteins and their annotated locations for XP_011239939.1

      Conserved Domains (1) summary
      cl28910
      Location:54591
      MFS; Major Facilitator Superfamily

    RNA

    1. XR_004933991.1 RNA Sequence

    Support Center