Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cpn1 carboxypeptidase N, polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 93721, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cpn1provided by MGI
    Official Full Name
    carboxypeptidase N, polypeptide 1provided by MGI
    Primary source
    MGI:MGI:2135874
    See related
    Ensembl:ENSMUSG00000025196
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C; CPN; 0610011F20Rik
    Expression
    Biased expression in liver adult (RPKM 130.6), liver E18 (RPKM 106.8) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cpn1 in Genome Data Viewer
    Location:
    19 C3; 19 36.68 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (43944746..43974990, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (43956307..43986551, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (44030797..44061010, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene dynamin binding protein Neighboring gene predicted gene, 24400 Neighboring gene predicted gene, 50217 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 23 Neighboring gene ER lipid raft associated 1 Neighboring gene uracil DNA glycosylase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables carboxypeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in bradykinin catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptide metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to glucocorticoid ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    carboxypeptidase N catalytic chain
    Names
    anaphylatoxin inactivator
    carboxypeptidase N small subunit
    carboxypeptidase N, polypeptide 1, 50kD
    kininase I
    NP_109628.1
    XP_011245709.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030703.2NP_109628.1  carboxypeptidase N catalytic chain precursor

      See identical proteins and their annotated locations for NP_109628.1

      Status: VALIDATED

      Source sequence(s)
      AF326477
      Consensus CDS
      CCDS29840.1
      UniProtKB/Swiss-Prot
      Q9JJN5
      Related
      ENSMUSP00000026210.5, ENSMUST00000026210.5
      Conserved Domains (2) summary
      cd11308
      Location:341415
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
      cl11393
      Location:25337
      Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      43944746..43974990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247407.1XP_011245709.1  carboxypeptidase N catalytic chain isoform X1

      Conserved Domains (2) summary
      cd11308
      Location:347421
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
      cl11393
      Location:25343
      Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins
    Support Center