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    Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 [ Mus musculus (house mouse) ]

    Gene ID: 13119, updated on 6-May-2021

    Summary

    Official Symbol
    Cyp4a14provided by MGI
    Official Full Name
    cytochrome P450, family 4, subfamily a, polypeptide 14provided by MGI
    Primary source
    MGI:MGI:1096550
    See related
    Ensembl:ENSMUSG00000028715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI314743
    Expression
    Biased expression in liver adult (RPKM 119.3), liver E18 (RPKM 97.4) and 1 other tissue See more
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    Genomic context

    See Cyp4a14 in Genome Data Viewer
    Location:
    4 D1; 4 53.04 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (115343397..115353355, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (115486200..115496158, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (115158805..115168746, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily a, polypeptide 30b Neighboring gene predicted gene 12833 Neighboring gene predicted gene, 52676 Neighboring gene cytochrome P450, family 4, subfamily a, polypeptide 10 Neighboring gene cytochrome P450, family 4, subfamily b, polypeptide 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC107660

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alkane 1-monooxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables alkane 1-monooxygenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables arachidonic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables arachidonic acid monooxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables arachidonic acid monooxygenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables fatty acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in arachidonic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in icosanoid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in kidney development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in lauric acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in linoleic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 4A14
    Names
    CYPIVA14
    cytochrome P450, 4a14
    cytochrome P450-LA-omega 3
    lauric acid hydroxylase
    lauric acid omega-hydroxylase 3
    long-chain fatty acid omega-monooxygenase
    NP_031848.1
    XP_006502787.2
    XP_017175435.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007822.2NP_031848.1  cytochrome P450 4A14

      See identical proteins and their annotated locations for NP_031848.1

      Status: VALIDATED

      Source sequence(s)
      AK165452, BC089609, BF322553
      Consensus CDS
      CCDS18491.1
      UniProtKB/Swiss-Prot
      O35728
      Related
      ENSMUSP00000030487.3, ENSMUST00000030487.3
      Conserved Domains (1) summary
      pfam00067
      Location:52501
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      115343397..115353355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502724.3XP_006502787.2  cytochrome P450 4A14 isoform X2

      Conserved Domains (1) summary
      pfam00067
      Location:52421
      p450; Cytochrome P450
    2. XM_017319946.2XP_017175435.1  cytochrome P450 4A14 isoform X1

      Conserved Domains (1) summary
      pfam00067
      Location:52452
      p450; Cytochrome P450
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