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    Abhd3 abhydrolase domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 106861, updated on 22-Aug-2021

    Summary

    Official Symbol
    Abhd3provided by MGI
    Official Full Name
    abhydrolase domain containing 3provided by MGI
    Primary source
    MGI:MGI:2147183
    See related
    Ensembl:ENSMUSG00000002475
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LAB; LABH3; AA675331
    Expression
    Broad expression in cerebellum adult (RPKM 12.2), liver adult (RPKM 11.7) and 20 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Abhd3 in Genome Data Viewer
    Location:
    18; 18 A1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (10644411..10706784, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (10644411..10706783, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (10644409..10706694, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 1 Neighboring gene small nuclear ribonucleoprotein D1 Neighboring gene RIKEN cDNA 4930563E18 gene Neighboring gene mindbomb E3 ubiquitin protein ligase 1 Neighboring gene predicted gene, 25116

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-acyl-2-lysophosphatidylserine acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acetylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables acylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylserine 1-acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipase A1 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phospholipase A1 activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables short-chain carboxylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cellular lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in medium-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in medium-chain fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phosphatidylcholine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phosphatidylcholine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in phosphatidylcholine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phospholipase ABHD3
    Names
    abhydrolase domain-containing protein 3
    lung alpha/beta hydrolase 3
    mmLABH3
    NP_598891.1
    XP_011245095.1
    XP_011245096.1
    XP_036016808.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134130.1NP_598891.1  phospholipase ABHD3

      See identical proteins and their annotated locations for NP_598891.1

      Status: VALIDATED

      Source sequence(s)
      AF429302
      Consensus CDS
      CCDS29057.1
      UniProtKB/Swiss-Prot
      Q91ZH7
      Related
      ENSMUSP00000113137.3, ENSMUST00000117828.9
      Conserved Domains (2) summary
      PLN02511
      Location:39403
      PLN02511; hydrolase
      cl21494
      Location:92398
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      10644411..10706784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160915.1XP_036016808.1  phospholipase ABHD3 isoform X1

      Conserved Domains (1) summary
      PLN02511
      Location:18311
      PLN02511; hydrolase
    2. XM_011246793.3XP_011245095.1  phospholipase ABHD3 isoform X2

      Conserved Domains (1) summary
      PLN02511
      Location:39223
      PLN02511; hydrolase
    3. XM_011246794.3XP_011245096.1  phospholipase ABHD3 isoform X3

      Conserved Domains (1) summary
      PLN02511
      Location:39190
      PLN02511; hydrolase

    RNA

    1. XR_004939811.1 RNA Sequence

    2. XR_385966.5 RNA Sequence

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