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    Zbtb4 zinc finger and BTB domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 75580, updated on 28-Sep-2021

    Summary

    Official Symbol
    Zbtb4provided by MGI
    Official Full Name
    zinc finger and BTB domain containing 4provided by MGI
    Primary source
    MGI:MGI:1922830
    See related
    Ensembl:ENSMUSG00000018750
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1538; 2310026P19Rik; 9230111I22Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 27.8), mammary gland adult (RPKM 15.4) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zbtb4 in Genome Data Viewer
    Location:
    11; 11 B3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69656738..69674852)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69765912..69784026)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69579414..69597528)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) II (DNA directed) polypeptide A Neighboring gene solute carrier family 35, member G3 Neighboring gene cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) Neighboring gene fibroblast growth factor 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyl-CpG binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables methyl-CpNpG binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger and BTB domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363178.1NP_001350107.1  zinc finger and BTB domain-containing protein 4

      Status: VALIDATED

      Source sequence(s)
      AL603707
      Consensus CDS
      CCDS36197.2
      Related
      ENSMUSP00000104280.2, ENSMUST00000108640.8
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    2. NM_029348.2NP_083624.2  zinc finger and BTB domain-containing protein 4

      See identical proteins and their annotated locations for NP_083624.2

      Status: VALIDATED

      Source sequence(s)
      AK147212, BE943927, CA325272, CJ106077
      Consensus CDS
      CCDS36197.2
      UniProtKB/Swiss-Prot
      Q5F293
      Related
      ENSMUSP00000104279.2, ENSMUST00000108639.8
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      69656738..69674852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249293.3XP_011247595.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_011247595.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    2. XM_006534390.4XP_006534453.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534453.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    3. XM_006534394.5XP_006534457.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534457.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    4. XM_006534391.5XP_006534454.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534454.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    5. XM_006534389.4XP_006534452.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534452.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
    6. XM_006534393.5XP_006534456.1  zinc finger and BTB domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534456.1

      UniProtKB/Swiss-Prot
      Q5F293
      Conserved Domains (5) summary
      sd00017
      Location:287307
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212228
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:739761
      zf-C2H2; Zinc finger, C2H2 type
      cd18195
      Location:12160
      BTB_POZ_ZBTB4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 4 (ZBTB4)
      pfam13913
      Location:211233
      zf-C2HC_2; zinc-finger of a C2HC-type
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